Mbth-like proteins in eukaryotic nrps-catalyzed processes

Roelof Ary Lans Bovenberg; Ulrike Maria Muller; Arnold Jacob Mathieu Driessen; Carsten Pohl; Reto Daniel Zwahlen

Mbth-like proteins in eukaryotic nrps-catalyzed processes

Roelof Ary Lans Bovenberg (Uitvinder), Ulrike Maria Muller (Uitvinder), Arnold Jacob Mathieu Driessen (Uitvinder), Carsten Pohl (Uitvinder), Reto Daniel Zwahlen (Uitvinder)

Onderzoeksoutput: Patent

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The present invention relates to a method to improve the production of a secondary metabolite catalyzed by a non-ribosomal peptide synthetase comprising contacting in a eukaryotic host a eukaryotic non-ribosomal peptide synthetase with an MbtH-like protein. The present invention further relates to a composition comprising a eukaryotic non-ribosomal peptide synthetase that is not a hybrid and a prokaryotic MbtH and to a eukaryotic host cell comprising a non-ribosomal peptide synthetase and a polynucleotide allowing the expression of an MbtH-like protein.

Originele taal-2	English
Octrooinummer	WO2017178624
Prioriteitsdatum	14/04/2016
Status	Published - 19-okt.-2017

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https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=WO&NR=2017178624A1&KC=A1&FT=D&ND=3&date=20171019&DB=&locale=en_EP

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title = "Mbth-like proteins in eukaryotic nrps-catalyzed processes",

abstract = "The present invention relates to a method to improve the production of a secondary metabolite catalyzed by a non-ribosomal peptide synthetase comprising contacting in a eukaryotic host a eukaryotic non-ribosomal peptide synthetase with an MbtH-like protein. The present invention further relates to a composition comprising a eukaryotic non-ribosomal peptide synthetase that is not a hybrid and a prokaryotic MbtH and to a eukaryotic host cell comprising a non-ribosomal peptide synthetase and a polynucleotide allowing the expression of an MbtH-like protein.",

author = "Bovenberg, {Roelof Ary Lans} and Muller, {Ulrike Maria} and Driessen, {Arnold Jacob Mathieu} and Carsten Pohl and Zwahlen, {Reto Daniel}",

year = "2017",

month = oct,

day = "19",

language = "English",

type = "Patent",

note = "WO2017178624",

}

TY - PAT

T1 - Mbth-like proteins in eukaryotic nrps-catalyzed processes

AU - Bovenberg, Roelof Ary Lans

AU - Muller, Ulrike Maria

AU - Driessen, Arnold Jacob Mathieu

AU - Pohl, Carsten

AU - Zwahlen, Reto Daniel

PY - 2017/10/19

Y1 - 2017/10/19

N2 - The present invention relates to a method to improve the production of a secondary metabolite catalyzed by a non-ribosomal peptide synthetase comprising contacting in a eukaryotic host a eukaryotic non-ribosomal peptide synthetase with an MbtH-like protein. The present invention further relates to a composition comprising a eukaryotic non-ribosomal peptide synthetase that is not a hybrid and a prokaryotic MbtH and to a eukaryotic host cell comprising a non-ribosomal peptide synthetase and a polynucleotide allowing the expression of an MbtH-like protein.

AB - The present invention relates to a method to improve the production of a secondary metabolite catalyzed by a non-ribosomal peptide synthetase comprising contacting in a eukaryotic host a eukaryotic non-ribosomal peptide synthetase with an MbtH-like protein. The present invention further relates to a composition comprising a eukaryotic non-ribosomal peptide synthetase that is not a hybrid and a prokaryotic MbtH and to a eukaryotic host cell comprising a non-ribosomal peptide synthetase and a polynucleotide allowing the expression of an MbtH-like protein.

M3 - Patent

M1 - WO2017178624

ER -