Samenvatting
The invention relates to means and methods for the modulation of lipid metabolism in an individual. Among others, it relates to a novel regulator of levels of plasma lipids and hepatic lipids and the use thereof for therapeutic intervention. Provided is a modulator of the Small leucine-rich protein 1 (human) (SMLR1) gene, a SMLR1 gene product, and/or a transcriptional regulator of SMLR1. Also provided is the use of the SMLR1 gene, a SMLR1 gene product, and/or a transcriptional regulator of SMLR1, as target in a method of modulating lipid metabolism in a subject.
Originele taal-2 | English |
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Octrooinummer | WO2021154079 |
Prioriteitsdatum | 29/01/2020 |
Indieningsdatum | 29/01/2021 |
Status | Published - 5-aug.-2021 |