Method for the production of primary amines

Kai-Uwe Baldenius; Klaus Ditrich; Michael  Breurer; Vaidotas Navickas; Dick Janssen; Sebastian Bartsch; Ciprian Crismaru

Method for the production of primary amines

Kai-Uwe Baldenius (Uitvinder), Klaus Ditrich (Uitvinder), Michael Breurer (Uitvinder), Vaidotas Navickas (Uitvinder), Dick Janssen (Uitvinder), Sebastian Bartsch (Uitvinder), Ciprian Crismaru (Uitvinder)

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The present invention relates to a novel enzymatically catalyzed method for the production of aliphatic primary amines, which method comprises the enzymatic oxidation of a primary aliphatic alcohol catalyzed by an alcohol dehydrogenase, amination of the resulting oxocompound catalyzed by a transaminase and optionally coupled with an enzymatically catalyzed regeneration of the consumed cofactor; recombinant expression systems and microorganisms procuring the required enzyme activities; and bioreactors for performing such methods; as well as the use of the obtained amines in organic synthesis, in particular for preparing organic polymers.

Originele taal-2	English
Octrooinummer	WO2014041011
Prioriteitsdatum	11/09/2012
Status	Published - 20-mrt.-2014

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https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=WO&NR=2014041011A2&KC=A2&FT=D&ND=3&date=20140320&DB=&locale=en_EP

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title = "Method for the production of primary amines",

abstract = "The present invention relates to a novel enzymatically catalyzed method for the production of aliphatic primary amines, which method comprises the enzymatic oxidation of a primary aliphatic alcohol catalyzed by an alcohol dehydrogenase, amination of the resulting oxocompound catalyzed by a transaminase and optionally coupled with an enzymatically catalyzed regeneration of the consumed cofactor; recombinant expression systems and microorganisms procuring the required enzyme activities; and bioreactors for performing such methods; as well as the use of the obtained amines in organic synthesis, in particular for preparing organic polymers.",

keywords = " primary amines, alcohol dehydrogenase, transaminase",

author = "Kai-Uwe Baldenius and Klaus Ditrich and Michael Breurer and Vaidotas Navickas and Dick Janssen and Sebastian Bartsch and Ciprian Crismaru",

year = "2014",

month = mar,

day = "20",

language = "English",

type = "Patent",

note = "WO2014041011",

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TY - PAT

T1 - Method for the production of primary amines

AU - Baldenius, Kai-Uwe

AU - Ditrich, Klaus

AU - Breurer, Michael

AU - Navickas, Vaidotas

AU - Janssen, Dick

AU - Bartsch, Sebastian

AU - Crismaru, Ciprian

PY - 2014/3/20

Y1 - 2014/3/20

N2 - The present invention relates to a novel enzymatically catalyzed method for the production of aliphatic primary amines, which method comprises the enzymatic oxidation of a primary aliphatic alcohol catalyzed by an alcohol dehydrogenase, amination of the resulting oxocompound catalyzed by a transaminase and optionally coupled with an enzymatically catalyzed regeneration of the consumed cofactor; recombinant expression systems and microorganisms procuring the required enzyme activities; and bioreactors for performing such methods; as well as the use of the obtained amines in organic synthesis, in particular for preparing organic polymers.

AB - The present invention relates to a novel enzymatically catalyzed method for the production of aliphatic primary amines, which method comprises the enzymatic oxidation of a primary aliphatic alcohol catalyzed by an alcohol dehydrogenase, amination of the resulting oxocompound catalyzed by a transaminase and optionally coupled with an enzymatically catalyzed regeneration of the consumed cofactor; recombinant expression systems and microorganisms procuring the required enzyme activities; and bioreactors for performing such methods; as well as the use of the obtained amines in organic synthesis, in particular for preparing organic polymers.

KW - primary amines

KW - alcohol dehydrogenase

KW - transaminase

M3 - Patent

M1 - WO2014041011

ER -