Method for the production of primary amines

Kai-Uwe Baldenius (Uitvinder), Klaus Ditrich (Uitvinder), Michael Breurer (Uitvinder), Vaidotas Navickas (Uitvinder), Dick Janssen (Uitvinder), Sebastian Bartsch (Uitvinder), Ciprian Crismaru (Uitvinder)



The present invention relates to a novel enzymatically catalyzed method for the production of aliphatic primary amines, which method comprises the enzymatic oxidation of a primary aliphatic alcohol catalyzed by an alcohol dehydrogenase, amination of the resulting oxocompound catalyzed by a transaminase and optionally coupled with an enzymatically catalyzed regeneration of the consumed cofactor; recombinant expression systems and microorganisms procuring the required enzyme activities; and bioreactors for performing such methods; as well as the use of the obtained amines in organic synthesis, in particular for preparing organic polymers.
Originele taal-2English
StatusPublished - 20-mrt.-2014

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