@inproceedings{6b262185bf7c43ceac051a6a929abd16,
title = "Micro magnetic resonance imaging of murine liver tissue slices on a microfluidic perfusion device",
abstract = "Micro-MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) spectroscopy are used to image and study metabolic activity of precision-cut liver slices (PCLS) on a microfluidic perfusion device. The imaging experiments were performed under static medium conditions while metabolic activity was monitored under continuous flow of medium. LDH (Lactate dehydrogenase) leakage assay was performed to assess the tissue viability on different days. MR images having ~30 (μm)2 in-plane resolution are recorded. This method could be used to culture and monitor PCLS non-invasively.",
keywords = "Micro-MRI, NMR, PCLS",
author = "Manvendra Sharma and Bishnubrata Patra and William Hale and Karsten, {Ruby E.H.} and Salentijn, {Gert I.J.} and Maciej Grajewski and Erwin Fuhrer and Anna Zakhurdaeva and Dario Mager and Jan Korvink and Peter Olinga and Elisabeth Verpoorte and Marcel Utz",
note = "Funding Information: This work was funded by H2020-FET Open TISuMR (#737043). Publisher Copyright: Copyright {\textcopyright} (2018) by Chemical and Biological Microsystems Society. All rights reserved. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.; 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 ; Conference date: 11-11-2018 Through 15-11-2018",
year = "2018",
language = "English",
series = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018",
publisher = "Chemical and Biological Microsystems Society ",
pages = "1722--1724",
booktitle = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018",
}