Microbial Characteristics of Peri-Implantitis: A Case-Control Study

Y C M de Waal*, H V L C Eijsbouts, E G Winkel, A J van Winkelhoff

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

33 Citaten (Scopus)


BACKGROUND: Aim of this case-control study was to compare oral microbiological characteristics of subjects with healthy peri-implant conditions and subjects with peri-implantitis and to explore the influence of various patient-related and implant-related factors on the microbiological characteristics.

METHODS: Peri-implant submucosal microbial samples were collected from 85 patients with peri-implantitis (cases) and from 69 patients with only implants with healthy peri-implant conditions (controls). Samples were analyzed using culturing techniques. Multivariable logistic regression was used to explore the association of disease status and various patient- and implant-related factors (gender, patient age, smoking, number of remaining teeth, percentage of teeth with bone loss, implant function time, implant surface and presence of plaque) with microbiological characteristics.

RESULTS: Peri-implant disease status was significantly associated with the submucosal presence of P. gingivalis, P. intermedia, T. forsythia, and F. nucleatum. The association with disease status was most obvious for P. intermedia (OR 15.1, 95% CI [5.1, 45.3]) and T. forsythia (OR 13.3, 95% CI [5.4, 32.5]). The prevalence of A. actinomycetemcomitans and Staphylococcus species was very low.

CONCLUSIONS: The periodontal pathogens P. gingivalis, P. intermedia, T. forsythia and F. nucleatum are associated with peri-implantitis. A. actinomycetemcomitans and Staphylococcus species do not seem to play an important role in peri-implantitis.

Originele taal-2English
Pagina's (van-tot)209-217
Aantal pagina's9
TijdschriftJournal of Periodontology
Nummer van het tijdschrift2
Vroegere onlinedatum26-sep.-2016
StatusPublished - feb.-2017


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