Microbiome Modulation of the Host Adaptive Immunity through Bile Acid Modification

Folkert Kuipers*, Jan Freark de Boer, Bart Staels

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

1 Citaat (Scopus)

Samenvatting

The microbiome is well known to influence the immune response of the host. Song et al. now show that the microbiome modulates adaptive immunity in mice through formation of bile acid species acting on RORγ+ regulatory T cells via the Vitamin D Receptor, thereby lowering the vulnerability for chemically induced colitis.

Originele taal-2English
Pagina's (van-tot)445-447
Aantal pagina's3
TijdschriftCell metabolism
Volume31
Nummer van het tijdschrift3
DOI's
StatusPublished - 3-mrt-2020

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