Modification of papain with a NAD(P)H analogue. Reactivity towards charged substrates and enhanced stability towards acid catalyzed hydration

Jaap Broos; Richard M. Kellogg

doi:10.1002/recl.19901090406

Modification of papain with a NAD(P)H analogue. Reactivity towards charged substrates and enhanced stability towards acid catalyzed hydration

Jaap Broos^*, Richard M. Kellogg

^*Corresponding author voor dit werk

Onderzoeksoutput › Academic › peer review

2 Citaten (Scopus)

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An N-alkylnicotinamidium salt has been linked covalently to Cys 25 of papain and thereafter reduced to the 1,4-dihydro form. Reactions of this material have been examined.

Originele taal-2	English
Pagina's (van-tot)	299-301
Aantal pagina's	3
Tijdschrift	Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands Chemical Society
Volume	109
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1002/recl.19901090406
Status	Published - apr.-1990

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@article{4aade025611a404aa132128886688e79,

title = "Modification of papain with a NAD(P)H analogue. Reactivity towards charged substrates and enhanced stability towards acid catalyzed hydration",

abstract = "An N-alkylnicotinamidium salt has been linked covalently to Cys 25 of papain and thereafter reduced to the 1,4-dihydro form. Reactions of this material have been examined.",

author = "Jaap Broos and Kellogg, {Richard M.}",

year = "1990",

month = apr,

doi = "10.1002/recl.19901090406",

language = "English",

volume = "109",

pages = "299--301",

journal = "Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands Chemical Society",

issn = "0165-0513",

publisher = "ELSEVIER SCIENCE BV",

number = "4",

}

TY - JOUR

T1 - Modification of papain with a NAD(P)H analogue. Reactivity towards charged substrates and enhanced stability towards acid catalyzed hydration

AU - Broos, Jaap

AU - Kellogg, Richard M.

PY - 1990/4

Y1 - 1990/4

N2 - An N-alkylnicotinamidium salt has been linked covalently to Cys 25 of papain and thereafter reduced to the 1,4-dihydro form. Reactions of this material have been examined.

AB - An N-alkylnicotinamidium salt has been linked covalently to Cys 25 of papain and thereafter reduced to the 1,4-dihydro form. Reactions of this material have been examined.

U2 - 10.1002/recl.19901090406

DO - 10.1002/recl.19901090406

M3 - Comment/Letter to the editor

SN - 0165-0513

VL - 109

SP - 299

EP - 301

JO - Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands Chemical Society

JF - Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands Chemical Society

IS - 4

ER -

Modification of papain with a NAD(P)H analogue. Reactivity towards charged substrates and enhanced stability towards acid catalyzed hydration

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