TY - JOUR
T1 - Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin
T2 - A narrative review
AU - Hentzen, Judith E. K. R.
AU - de Jongh, Steven J.
AU - Hemmer, Patrick H. J.
AU - van der Plas, Willemijn Y.
AU - van Dam, Gooitzen M.
AU - Kruijff, Schelto
PY - 2018/8/1
Y1 - 2018/8/1
N2 - Patients with peritoneal carcinomatosis (PC) from colorectal origin may undergo cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) as a curative approach. One major prognostic factor that affects survival is completeness of cytoreduction. Molecular Fluorescence Guided Surgery (MFGS) is a novel intraoperative imaging technique that may improve tumor identification in the future, potentially preventing over- and under-treatment in these patients. This narrative review outlines a chronological overview of MFGS development in patients with PC of colorectal origin.
AB - Patients with peritoneal carcinomatosis (PC) from colorectal origin may undergo cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) as a curative approach. One major prognostic factor that affects survival is completeness of cytoreduction. Molecular Fluorescence Guided Surgery (MFGS) is a novel intraoperative imaging technique that may improve tumor identification in the future, potentially preventing over- and under-treatment in these patients. This narrative review outlines a chronological overview of MFGS development in patients with PC of colorectal origin.
KW - colorectal cancer
KW - molecular fluorescence-guided surgery
KW - peritoneal carcinomatosis
KW - review
KW - HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY
KW - ENDOTHELIAL GROWTH-FACTOR
KW - GLOBAL CANCER STATISTICS
KW - SENTINEL LYMPH-NODE
KW - INDOCYANINE-GREEN
KW - CYTOREDUCTIVE SURGERY
KW - PHOTODYNAMIC THERAPY
KW - CARCINOEMBRYONIC ANTIGEN
KW - PHASE-I
KW - SYSTEMIC CHEMOTHERAPY
U2 - 10.1002/jso.25106
DO - 10.1002/jso.25106
M3 - Review article
VL - 118
SP - 332
EP - 343
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
SN - 0022-4790
IS - 2
ER -