Multi-domain cognitive impairments at school age in very preterm-born children compared to term-born peers

Elise Roze*, Sijmen A. Reijneveld, Roy E. Stewart, Arend F. Bos

*Bijbehorende auteur voor dit werk

Onderzoeksoutput: ArticleAcademicpeer review

3 Downloads (Pure)

Samenvatting

Background Preterm infants are at risk for functional impairments in motor, cognitive, and behavioral development that may persist into childhood. The aim of this study was to determine the co-occurrence of cognitive impairments in multiple cognitive domains at school age in very preterm born children compared to term-born children. Methods Comparative study including 60 very preterm-born children (gestational age = 2), versus 3% of the controls (odds ratio, OR 4.65, 95%-confidence interval, CI 1.33-16.35). For multiple suspect-abnormal cognitive outcomes, rates were 55% versus 25% (OR 3.02, 95%-CI 1.49-6.12). We found no pattern of co-occurrence of cognitive impairments among preterm children that deviated from term-born controls. However, low performance IQ was more frequently accompanied by additional cognitive impairments in preterms than in controls (OR 5.43, 95%-CI 1.75-16.81). Conclusions A majority of preterm children showed co-occurrence of impairments in multiple cognitive domains, but with no specific pattern of impairments. The occurrence of multi-domain cognitive impairments is higher in preterms but this seems to reflect a general increase, not one with a pattern specific for preterm-born children.

Originele taal-2English
Artikelnummer169
Aantal pagina's9
TijdschriftBMC Pediatrics
Volume21
Nummer van het tijdschrift1
DOI's
StatusE-pub ahead of print - 13-apr-2021

Citeer dit