N-alkylated amino acids and oligopeptides, uses thereof and methods for providing them.

Katalin Barta; Tao Yan; Bernard Lucas Feringa

N-alkylated amino acids and oligopeptides, uses thereof and methods for providing them.

Katalin Barta (Uitvinder), Tao Yan (Uitvinder), Bernard Lucas Feringa (Uitvinder)

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The invention relates to the synthesis of amphiphilic amino acid derivatives, in particular to a method for the N-alkylation of an unprotected amino acid or the N-terminus of an oligopeptide substrate, comprising reacting said unprotected amino acid or oligopeptide substrate with an alcohol, e.g. a fatty alcohol, in the presence of a homogeneous transition metal catalyst.

Originele taal-2	English
Octrooinummer	WO2018178397
Prioriteitsdatum	30/03/2017
Status	Published - 4-okt.-2018

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@misc{84f314d7328e4286bd3a5ab7db25aa57,

title = "N-alkylated amino acids and oligopeptides, uses thereof and methods for providing them.",

abstract = "The invention relates to the synthesis of amphiphilic amino acid derivatives, in particular to a method for the N-alkylation of an unprotected amino acid or the N-terminus of an oligopeptide substrate, comprising reacting said unprotected amino acid or oligopeptide substrate with an alcohol, e.g. a fatty alcohol, in the presence of a homogeneous transition metal catalyst.",

author = "Katalin Barta and Tao Yan and Feringa, \{Bernard Lucas\}",

year = "2018",

month = oct,

day = "4",

language = "English",

type = "Patent",

note = "WO2018178397",

}

TY - PAT

T1 - N-alkylated amino acids and oligopeptides, uses thereof and methods for providing them.

AU - Barta, Katalin

AU - Yan, Tao

AU - Feringa, Bernard Lucas

PY - 2018/10/4

Y1 - 2018/10/4

N2 - The invention relates to the synthesis of amphiphilic amino acid derivatives, in particular to a method for the N-alkylation of an unprotected amino acid or the N-terminus of an oligopeptide substrate, comprising reacting said unprotected amino acid or oligopeptide substrate with an alcohol, e.g. a fatty alcohol, in the presence of a homogeneous transition metal catalyst.

AB - The invention relates to the synthesis of amphiphilic amino acid derivatives, in particular to a method for the N-alkylation of an unprotected amino acid or the N-terminus of an oligopeptide substrate, comprising reacting said unprotected amino acid or oligopeptide substrate with an alcohol, e.g. a fatty alcohol, in the presence of a homogeneous transition metal catalyst.

M3 - Patent

M1 - WO2018178397

ER -

N-alkylated amino acids and oligopeptides, uses thereof and methods for providing them.

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