New PET technologies: performance, image quality, and clinical implications

Joyce van Sluis

doi:10.33612/diss.254107383

New PET technologies: performance, image quality, and clinical implications

Joyce van Sluis

Onderzoeksoutput: Thesis fully internal (DIV)

286 Downloads (Pure)

Samenvatting

The most specific and sensitive imaging modality for visualizing and measuring human (patho)physiology in vivo is Positron Emission Tomography (PET). PET is a firmly established biomedical imaging modality with applications in routine clinical diagnostic imaging, but also in research, including clinical trials. Over the past years, PET technology development brought new innovative PET systems to the commercial market: silicon photomultiplier (SiPM)-based or ‘digital’ PET systems, and large axial field-of-view or ‘total body’ PET systems. This thesis describes the technical performance characteristics of these new PET technologies and, in addition, associated optimization of image quality and activity administration is reported. Furthermore, clinical implications and future perspectives regarding these innovations in the field of nuclear medicine and molecular imaging and other medical disciplines are discussed.

Originele taal-2	English
Kwalificatie	Doctor of Philosophy
Toekennende instantie	Rijksuniversiteit Groningen
Begeleider(s)/adviseur	Boellaard, Ronald, Supervisor Noordzij, Walter, Co-supervisor Brouwers, Adrienne, Co-supervisor
Datum van toekenning	7-dec.-2022
Plaats van publicatie	[Groningen]
Uitgever	University of Groningen
Gedrukte ISBN's	978-90-832523-2-2
Elektronische ISBN's	978-90-832523-3-9
DOI's	https://doi.org/10.33612/diss.254107383
Status	Published - 2022

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10.33612/diss.254107383

Title and contentsFinal publisher's version, 0,99 MB
Chapter 1Final publisher's version, 1,27 MB
Chapter 2Final publisher's version, 1,53 MB
Chapter 3Final publisher's version, 1,87 MB
Chapter 4Final publisher's version, 2,14 MB
Chapter 5Final publisher's version, 2,01 MB
Chapter 6Final publisher's version, 2,17 MB
Chapter 7Final publisher's version, 1,27 MB
Chapter 8Final publisher's version, 1,93 MB
Chapter 9Final publisher's version, 1,52 MB
Chapter 10Final publisher's version, 2,05 MB
Chapter 11Final publisher's version, 1,55 MB
Chapter 12Final publisher's version, 1,32 MB
Chapter 13Final publisher's version, 1,45 MB
AppendicesFinal publisher's version, 1,47 MB
Complete thesisFinal publisher's version, 6,06 MB
PropositionsFinal publisher's version, 907 KB

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