Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

Minseok Kwak; Andreas Herrmann

doi:10.1039/c1cs15138j

Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

Minseok Kwak, Andreas Herrmann^*

^*Corresponding author voor dit werk

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This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.

Originele taal-2	English
Pagina's (van-tot)	5745-5755
Aantal pagina's	11
Tijdschrift	Chemical Society Reviews
Volume	40
Nummer van het tijdschrift	12
DOI's	https://doi.org/10.1039/c1cs15138j
Status	Published - 2011

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abstract = "This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.",

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AB - This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.

KW - BLOCK-COPOLYMER MICELLES

KW - MODIFIED OLIGONUCLEOTIDES

KW - CYCLOADDITION REACTION

KW - MOLECULAR RECOGNITION

KW - FORCE MICROSCOPY

KW - DNA-ORIGAMI

KW - NANOPARTICLES

KW - SHAPES

KW - FUSION

KW - CHEMISTRY

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Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

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