One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice: A pragmatic randomised controlled trial over 12 months

Anne M M Loohuis; Henk Van Der Worp; Nienke J Wessels; Janny H Dekker; Marijke C Ph Slieker-Ten Hove; Marjolein Y Berger; Karin M Vermeulen; Marco H Blanker

doi:10.1111/1471-0528.16875

One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice: A pragmatic randomised controlled trial over 12 months

Anne M M Loohuis^*, Henk Van Der Worp, Nienke J Wessels, Janny H Dekker, Marijke C Ph Slieker-Ten Hove, Marjolein Y Berger, Karin M Vermeulen, Marco H Blanker

^*Bijbehorende auteur voor dit werk

Onderzoeksoutput › Academic › peer review

Samenvatting

OBJECTIVE: To assess the long-term effectiveness of app-based treatment for female stress, urgency, or mixed urinary incontinence (UI) compared to care-as-usual in primary care.

DESIGN: A pragmatic, randomised controlled, superiority trial.

SETTING: Primary care in the Netherlands from 2015 to 2018, follow-up at 12 months.

POPULATION: Women with ≥2 UI-episodes per week, access to mobile apps, wanting treatment. 262 women randomised equally to app or care-as-usual; 89 (68%) and 83 (63%) attended one year follow-up.

INTERVENTIONS: The standalone app included conservative management for UI with motivation aids (e.g., reminders). Care-as-usual delivered according to the Dutch GP guideline for UI.

MAIN OUTCOME MEASURES: Effectiveness assessed by the change in symptom severity score (ICIQ-UI-SF) and the change in quality of life (ICIQ-LUTS-QoL) with linear regression on an intention-to-treat basis.

RESULTS: Clinically relevant improvement of UI severity for both app (-2.17 ± 2.81) and care-as-usual (-3.43 ± 3.6), with a non-significant mean difference of 0.903 (-0.66 to 1.871).

CONCLUSION: App-based treatment is a viable alternative to care-as-usual for UI in primary care in terms of effectiveness after one year.

Originele taal-2	English
Tijdschrift	BJOG : An International Journal of Obstetrics and Gynaecology
DOI's	https://doi.org/10.1111/1471-0528.16875
Status	E-pub ahead of print - 26-aug-2021

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10.1111/1471-0528.16875

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One year effectiveness of an app‐based treatment for urinary incontinence in comparison to care as usual in Dutch general practice_ A pragmatic randomised controlled trial over 12 months
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Loohuis, A. M. M., Van Der Worp, H., Wessels, N. J., Dekker, J. H., Slieker-Ten Hove, M. C. P., Berger, M. Y., Vermeulen, K. M., & Blanker, M. H. (2021). One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice: A pragmatic randomised controlled trial over 12 months. BJOG : An International Journal of Obstetrics and Gynaecology. https://doi.org/10.1111/1471-0528.16875

Loohuis, Anne M M ; Van Der Worp, Henk ; Wessels, Nienke J ; Dekker, Janny H ; Slieker-Ten Hove, Marijke C Ph ; Berger, Marjolein Y ; Vermeulen, Karin M ; Blanker, Marco H. / One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice : A pragmatic randomised controlled trial over 12 months. In: BJOG : An International Journal of Obstetrics and Gynaecology. 2021.

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title = "One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice: A pragmatic randomised controlled trial over 12 months",

abstract = "OBJECTIVE: To assess the long-term effectiveness of app-based treatment for female stress, urgency, or mixed urinary incontinence (UI) compared to care-as-usual in primary care.DESIGN: A pragmatic, randomised controlled, superiority trial.SETTING: Primary care in the Netherlands from 2015 to 2018, follow-up at 12 months.POPULATION: Women with ≥2 UI-episodes per week, access to mobile apps, wanting treatment. 262 women randomised equally to app or care-as-usual; 89 (68%) and 83 (63%) attended one year follow-up.INTERVENTIONS: The standalone app included conservative management for UI with motivation aids (e.g., reminders). Care-as-usual delivered according to the Dutch GP guideline for UI.MAIN OUTCOME MEASURES: Effectiveness assessed by the change in symptom severity score (ICIQ-UI-SF) and the change in quality of life (ICIQ-LUTS-QoL) with linear regression on an intention-to-treat basis.RESULTS: Clinically relevant improvement of UI severity for both app (-2.17 ± 2.81) and care-as-usual (-3.43 ± 3.6), with a non-significant mean difference of 0.903 (-0.66 to 1.871).CONCLUSION: App-based treatment is a viable alternative to care-as-usual for UI in primary care in terms of effectiveness after one year.",

author = "Loohuis, {Anne M M} and {Van Der Worp}, Henk and Wessels, {Nienke J} and Dekker, {Janny H} and {Slieker-Ten Hove}, {Marijke C Ph} and Berger, {Marjolein Y} and Vermeulen, {Karin M} and Blanker, {Marco H}",

year = "2021",

month = aug,

day = "26",

doi = "10.1111/1471-0528.16875",

language = "English",

journal = "BJOG : An International Journal of Obstetrics and Gynaecology",

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Loohuis, AMM , Van Der Worp, H , Wessels, NJ , Dekker, JH, Slieker-Ten Hove, MCP, Berger, MY , Vermeulen, KM & Blanker, MH 2021, 'One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice: A pragmatic randomised controlled trial over 12 months', BJOG : An International Journal of Obstetrics and Gynaecology. https://doi.org/10.1111/1471-0528.16875

One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice : A pragmatic randomised controlled trial over 12 months. / Loohuis, Anne M M ; Van Der Worp, Henk ; Wessels, Nienke J ; Dekker, Janny H; Slieker-Ten Hove, Marijke C Ph; Berger, Marjolein Y ; Vermeulen, Karin M ; Blanker, Marco H.

In: BJOG : An International Journal of Obstetrics and Gynaecology, 26.08.2021.

Onderzoeksoutput › Academic › peer review

TY - JOUR

T1 - One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice

T2 - A pragmatic randomised controlled trial over 12 months

AU - Loohuis, Anne M M

AU - Van Der Worp, Henk

AU - Wessels, Nienke J

AU - Dekker, Janny H

AU - Slieker-Ten Hove, Marijke C Ph

AU - Berger, Marjolein Y

AU - Vermeulen, Karin M

AU - Blanker, Marco H

PY - 2021/8/26

Y1 - 2021/8/26

N2 - OBJECTIVE: To assess the long-term effectiveness of app-based treatment for female stress, urgency, or mixed urinary incontinence (UI) compared to care-as-usual in primary care.DESIGN: A pragmatic, randomised controlled, superiority trial.SETTING: Primary care in the Netherlands from 2015 to 2018, follow-up at 12 months.POPULATION: Women with ≥2 UI-episodes per week, access to mobile apps, wanting treatment. 262 women randomised equally to app or care-as-usual; 89 (68%) and 83 (63%) attended one year follow-up.INTERVENTIONS: The standalone app included conservative management for UI with motivation aids (e.g., reminders). Care-as-usual delivered according to the Dutch GP guideline for UI.MAIN OUTCOME MEASURES: Effectiveness assessed by the change in symptom severity score (ICIQ-UI-SF) and the change in quality of life (ICIQ-LUTS-QoL) with linear regression on an intention-to-treat basis.RESULTS: Clinically relevant improvement of UI severity for both app (-2.17 ± 2.81) and care-as-usual (-3.43 ± 3.6), with a non-significant mean difference of 0.903 (-0.66 to 1.871).CONCLUSION: App-based treatment is a viable alternative to care-as-usual for UI in primary care in terms of effectiveness after one year.

AB - OBJECTIVE: To assess the long-term effectiveness of app-based treatment for female stress, urgency, or mixed urinary incontinence (UI) compared to care-as-usual in primary care.DESIGN: A pragmatic, randomised controlled, superiority trial.SETTING: Primary care in the Netherlands from 2015 to 2018, follow-up at 12 months.POPULATION: Women with ≥2 UI-episodes per week, access to mobile apps, wanting treatment. 262 women randomised equally to app or care-as-usual; 89 (68%) and 83 (63%) attended one year follow-up.INTERVENTIONS: The standalone app included conservative management for UI with motivation aids (e.g., reminders). Care-as-usual delivered according to the Dutch GP guideline for UI.MAIN OUTCOME MEASURES: Effectiveness assessed by the change in symptom severity score (ICIQ-UI-SF) and the change in quality of life (ICIQ-LUTS-QoL) with linear regression on an intention-to-treat basis.RESULTS: Clinically relevant improvement of UI severity for both app (-2.17 ± 2.81) and care-as-usual (-3.43 ± 3.6), with a non-significant mean difference of 0.903 (-0.66 to 1.871).CONCLUSION: App-based treatment is a viable alternative to care-as-usual for UI in primary care in terms of effectiveness after one year.

U2 - 10.1111/1471-0528.16875

DO - 10.1111/1471-0528.16875

M3 - Article

C2 - 34437756

JO - BJOG : An International Journal of Obstetrics and Gynaecology

JF - BJOG : An International Journal of Obstetrics and Gynaecology

SN - 1471-0528

ER -

Loohuis AMM , Van Der Worp H , Wessels NJ , Dekker JH, Slieker-Ten Hove MCP, Berger MY et al. One year effectiveness of an app-based treatment for urinary incontinence in comparison to care as usual in Dutch general practice: A pragmatic randomised controlled trial over 12 months. BJOG : An International Journal of Obstetrics and Gynaecology. 2021 aug 26. https://doi.org/10.1111/1471-0528.16875