Open-heart surgery at school age does not affect neurocognitive functioning

Rachel Van Der Rijken*, Gerdine Hulstijn-Dirkmaat, Floris Kraaimaat, Lida Nabuurs-Kohrman, Aagje Nijveld, Ben Maassen, Otto Daniëls

*Bijbehorende auteur voor dit werk

Onderzoeksoutput: ArticleAcademicpeer review

15 Citaten (Scopus)


Aims: Although neurocognitive problems after open-heart surgery for congenital heart disease are frequent, due to a shortage of prospective studies assessing neurocognitive functioning both before and after the procedure, the exact nature of the deficits usually remains unknown. The present study aims at assessing the neurocognitive effects of, in particular, cardiopulmonary bypass at school age. In addition, surgery-related risk factors for reduced neurocognitive outcome are explored. Methods and results: Participants were aged between 6 and 16 years. Forty-three children indicated for open-heart surgery and a comparison group of 19 children scheduled for interventional cardiac catheterization completed a neurocognitive assessment battery before and 1 year after their procedures. Forty healthy matched controls did so at a 1 year interval. The baseline-to-follow-up outcomes were similar in all three groups. The observed improvements most likely resulted from increased age and the repeated neurocognitive assessment. No risk factors for postsurgical neurocognitive deficits were identified. Conclusion: The present study demonstrates that at school age cardiac surgery using full-flow cardiopulmonary bypass does not affect neurocognitive functioning.

Originele taal-2English
Pagina's (van-tot)2681-2688
Aantal pagina's8
TijdschriftEuropean Heart Journal
Nummer van het tijdschrift21
StatusPublished - nov.-2008
Extern gepubliceerdJa

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