Optimizing CO2 field flooding during sternotomy: In vitro confirmation of the Karolinska studies

Mira Puthettu*, Stijn Vandenberghe, Spyros Balafas, Clelia Di Serio, Geni Singjeli, Alberto Pagnamenta, Stefanos Demertzis

*Corresponding author voor dit werk

Onderzoeksoutputpeer review

23 Downloads (Pure)


Although CO2 field-flooding was first used during cardiac surgery more than 60 years ago, its efficacy is still disputed. The invisible nature of the gas and the difficulty in determining the "safe" quantity to protect the patient are two of the main obstacles to overcome for its validation. Moreover, CO2 concentration in the chest cavity is highly sensitive to procedural aspects, such suction and hand movements. Based on our review of the existing literature, we identified four major factors that influence the intra-cavity CO2 concentration during open-heart surgery: type of delivery device (diffuser), delivery CO2 flow rate, diffuser position around the wound cavity, and its orientation inside the cavity. In this initial study, only steady state conditions were considered to establish a basic understanding on the effect of the four above-mentioned factors. Transient factors, such as suction or hand movements, will be reported separately.

Originele taal-2English
Aantal pagina's14
TijdschriftPLoS ONE
Nummer van het tijdschrift1
StatusPublished - 2024


Duik in de onderzoeksthema's van 'Optimizing CO2 field flooding during sternotomy: In vitro confirmation of the Karolinska studies'. Samen vormen ze een unieke vingerafdruk.

Citeer dit