Orthostatic hypotension, diabetes, and falling in older patients: a cross-sectional study

Kornelis J. J. van Hateren*, Nanne Kleefstra, Marco H. Blanker, Lielith J. Ubink-Veltmaat, Klaas H. Groenier, Sebastiaan Houweling, Adriaan M. Kemper, Klaas van der Meer, Henk J. G. Bilo

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

37 Citaten (Scopus)



Although orthostatic hypotension (OH) is more prevalent in old age, and in patients with diabetes, the prevalence of OH in older patients with type 2 diabetes mellitus is unknown.


To establish the prevalence of OH, and its association with falling, in home-dwelling older participants with and without type 2 diabetes.

Design and setting:

A cross-sectional study in primary care in the Netherlands.


A total of 352 patients with type 2 diabetes, and 211 without participated in this study. OH was defined as a fall in blood pressure of at least 20 mmHg systolic or 10 mmHg diastolic after either 1 or 3 minutes in an upright position. Feelings of dizziness, light-headedness, or faintness during the standing period were documented as orthostatic complaints. Fall risk was assessed with a validated risk profile instrument.


The prevalence of OH was 28% (95% CI = 24% to 33%) and 18% (95% CI = 13% to 23%) in participants with and without type 2 diabetes, respectively. OH was not related to falling, while the presence of orthostatic complaints in itself was associated with both previous fall incidents as well as a high fall risk, even after adjustment for OH. The adjusted odds ratios were 1.65 (95% CI = 1.00 to 2.72) and 8.21 (95% CI = 4.17 to 16.19), respectively.


OH is highly prevalent in home-dwelling older people with and without type 2 diabetes. Those with orthostatic complaints had an increased risk for falling, whereas those with OH were not.

Originele taal-2English
Pagina's (van-tot)e696-e702
Aantal pagina's7
TijdschriftBritish Journal of General Practice
Nummer van het tijdschrift603
StatusPublished - 1-okt-2012

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