TY - JOUR
T1 - Personality traits and coping strategies in recent-onset psychosis
T2 - Associations with symptom severity and psychosocial functioning
AU - PHAMOUS investigators
AU - PROGR-S Investigators
AU - Djordjevic, Matej
AU - Brink, Vera
AU - Wardenaar, Klaas J.
AU - Scholte-Stalenhoef, Anne Neeltje
AU - Visser, Ellen
AU - Knegtering, Henderikus
AU - Liemburg, Edith
AU - Castelein, Stynke
AU - Bartels-Velthuis, Agna A.
AU - Bruggeman, Richard
AU - Jörg, Frederike
AU - Pijnenborg, Gerdina H.M.
AU - van Driel, Catheleine
AU - Veling, Wim
N1 - Funding Information:
This project was funded by an internal research grant of University Medical Center Groningen to VB (M.D.-Ph.D. grant number 18-41 ), and by the participating mental health care institutions (Lentis Psychiatric Institute, GGZ Friesland, GGZ Drenthe, and the University Center for Psychiatry of the University Medical Center Groningen). As the PROGR-S and PHAMOUS data were collected as part of routine care, the funding parties were involved in selection of measurements and data collection. They did not have any influence on statistical analyses and interpretation, writing of the report or the decision to submit the article.
Publisher Copyright:
© 2022 The Authors
PY - 2022/12
Y1 - 2022/12
N2 - Background: Personality and coping may be related to symptom severity and psychosocial functioning in patients with recent-onset psychosis. This study aimed to investigate associations of personality traits and coping strategies with concurrent and follow-up symptom severity and functioning in those patients, and identify whether coping mediates relations between personality and symptoms or functioning.Methods: At baseline, 527 recent-onset psychosis patients (73 % male, mean age = 28 years) received assessments on personality (Neuroticism-Extraversion-Openness – Five-Factor Inventory), coping (Utrecht Coping List), symptom severity (Positive And Negative Syndrome Scale) and psychosocial functioning (Global Assessment of Functioning Scale). Of those, 149 also received symptom and functioning assessments at follow-up. Multivariable linear regression analyses were performed to assess cross-sectional associations of personality and coping with symptoms and functioning at baseline. Longitudinal associations of baseline personality and coping with follow-up symptomatic remission and functioning were analyzed with multivariable linear and binary logistic regression analyses, respectively. Lastly, it was investigated whether coping mediated associations between personality and symptoms or functioning.Results: Higher baseline Agreeableness (B = -0.019, [95%CI: −0.031; −0.007]) and Neuroticism (B = -0.017, [95%CI: −0.028; −0.006]) were associated with lower concurrent symptom severity. Reassuring Thoughts were associated with better functioning at baseline (B = 0.833, [95%CI: 0.272; 1.393]). Neither personality nor coping were associated with follow-up symptomatic remission or functioning. Coping did not mediate associations between personality and symptoms or functioning.Conclusion: Only the coping strategy Reassuring Thoughts is associated with better baseline functioning in patients with recent-onset psychosis. Personality traits seem to have limited clinically relevant relations with symptom severity or functioning.
AB - Background: Personality and coping may be related to symptom severity and psychosocial functioning in patients with recent-onset psychosis. This study aimed to investigate associations of personality traits and coping strategies with concurrent and follow-up symptom severity and functioning in those patients, and identify whether coping mediates relations between personality and symptoms or functioning.Methods: At baseline, 527 recent-onset psychosis patients (73 % male, mean age = 28 years) received assessments on personality (Neuroticism-Extraversion-Openness – Five-Factor Inventory), coping (Utrecht Coping List), symptom severity (Positive And Negative Syndrome Scale) and psychosocial functioning (Global Assessment of Functioning Scale). Of those, 149 also received symptom and functioning assessments at follow-up. Multivariable linear regression analyses were performed to assess cross-sectional associations of personality and coping with symptoms and functioning at baseline. Longitudinal associations of baseline personality and coping with follow-up symptomatic remission and functioning were analyzed with multivariable linear and binary logistic regression analyses, respectively. Lastly, it was investigated whether coping mediated associations between personality and symptoms or functioning.Results: Higher baseline Agreeableness (B = -0.019, [95%CI: −0.031; −0.007]) and Neuroticism (B = -0.017, [95%CI: −0.028; −0.006]) were associated with lower concurrent symptom severity. Reassuring Thoughts were associated with better functioning at baseline (B = 0.833, [95%CI: 0.272; 1.393]). Neither personality nor coping were associated with follow-up symptomatic remission or functioning. Coping did not mediate associations between personality and symptoms or functioning.Conclusion: Only the coping strategy Reassuring Thoughts is associated with better baseline functioning in patients with recent-onset psychosis. Personality traits seem to have limited clinically relevant relations with symptom severity or functioning.
KW - Coping
KW - Functioning
KW - Personality
KW - Psychosis
KW - Recent-onset
KW - Symptom
U2 - 10.1016/j.schres.2022.10.010
DO - 10.1016/j.schres.2022.10.010
M3 - Article
AN - SCOPUS:85142128399
SN - 0920-9964
VL - 250
SP - 143
EP - 151
JO - Schizophrenia Research
JF - Schizophrenia Research
ER -