Platelet-neutrophil interactions as drivers of inflammatory and thrombotic disease

Ton Lisman*

*Bijbehorende auteur voor dit werk

Onderzoeksoutputpeer review

144 Citaten (Scopus)
355 Downloads (Pure)


Neutrophils are well known for their role in infection and inflammatory disease and are first responders at sites of infection or injury. Platelets have an established role in hemostasis and thrombosis and are first responders at sites of vascular damage. However, neutrophils are increasingly recognized for their role in thrombosis, while the immunemodulatory properties of platelets are being increasingly studied. Platelets and neutrophils interact during infection, inflammation and thrombosis and modulate each other's functions. This review will discuss the consequences of platelet-neutrophil interactions in infection, thrombosis, atherosclerosis and tissue injury and repair.

Originele taal-2English
Pagina's (van-tot)567-576
Aantal pagina's10
TijdschriftCell and Tissue Research
Nummer van het tijdschrift3
StatusPublished - mrt.-2018

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