Poly(DL-lactide-epsilon-caprolactone) nerve guides perform better than autologous nerve grafts

WFA DenDunnen, B VanderLei, JM Schakenraad, [No Value] Stokroos, E Blaauw, AJ Pennings, PH Robinson, H. Bartels

OnderzoeksoutputAcademicpeer review

78 Citaten (Scopus)

Samenvatting

The aim of this study was to compare the speed and quality of nerve regeneration after reconstruction using a biodegradable nerve guide or an autologous nerve graft. We evaluated nerve regeneration using light microscopy, transmission electron microscopy and morphometric analysis. Nerve regeneration across a short nerve gap, after reconstruction using a biodegradable nerve guide, is faster and qualitatively better, when compared with nerve reconstruction using an autologous nerve graft. Therefore, we conclude that in the case of a short nerve gap (1 cm), reconstruction should be carried out using a biodegradable nerve guide constructed of a copolymer of DL-lactide and epsilon-caprolactone. (C) 1997 Wiley-Liss, Inc.

Originele taal-2English
Pagina's (van-tot)348-357
Aantal pagina's10
TijdschriftMicrosurgery
Volume17
Nummer van het tijdschrift7
StatusPublished - 1996

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