Polypeptides with permease activity

Paul Klaassen; Paulus Petrus De Waal; Rene Marcel De Jong; Arnold Jacob Mattieu Driessen; Jeroen Gerben Nijland; Hyun Yong Shin

Polypeptides with permease activity

Paul Klaassen (Uitvinder), Paulus Petrus De Waal (Uitvinder), Rene Marcel De Jong (Uitvinder), Arnold Jacob Mattieu Driessen (Uitvinder), Jeroen Gerben Nijland (Uitvinder), Hyun Yong Shin (Uitvinder)

Moleculaire Microbiologie

Onderzoeksoutput: Patent

Samenvatting

The invention relates to a polypeptide having one or more substitution corresponding to F85T/A/C/H/M/N, T89H/D/C/A/N, V187T/C/D/E/F/G/H/K/M/Q/R/S/W/Y, A191N/G/P/ C/D/F/H/I/K/Q/V/W/Y, Y214V/Q/G/L/M/N/P/R/S, Q215L/M/I/A/C/D/F/S, I218K/N/A/C/D/E/H/L, T219G/F/D/N, I222D/C/H/E/G/P/S/V/Y, Y226D/M/R/C/G/H/I/L/P/Q/T/W, Q338C/E/F/D/G/I/P/R/S/T/V/W/Y, M339N/V/D/E/H/K/P/Q/R/Y, The invention relates to a polypeptide having one or more substitution corresponding to T89C/Y, V187M/Q/C/G/Y, A191 l/K/D/C/E/N/W/R/P, Y214L/P, Q215D/E/S/M/L/C/F/A, 1218W, T219V/L/R/E, I222G/Y/M/P/S/W, Y226M/T/P/Q, Q338R/I/D/E/F/G/P, M339Y/E/N, Q341V/Y/S/H, Q342N/H/R/C/F/G/I/K/L/P/S/T/W, L343Y/Q/I/C/E/K/N/P/S, N346G/I, N347S/L/K/G/TA/, Y350E/S/Q, G373R/K/L/IWY, N376K/Q/A/C/D/E/I/M/P, T380Y/G/M/A/S/D/E/I/K/L/W, S383Y/WA//C/E/I/L/Q/R, F446H/D/I, T448/R/K/H/D/E/W, T449F/H/A/G/I/L/P/QA/, T451W/Y/S, W455D/K/E/P/Q, N478Q/I/F/G, or W479S/I/F/D/E/H/M/N/R/T/Y of SEQ ID NO:59 wherein the polypeptide is member of the Major Facilitator Superfamily (MFS).

Originele taal-2	English
Octrooinummer	WO2014195520
Prioriteitsdatum	13/12/2013
Status	Published - 11-dec.-2014

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@misc{5962bcfe1e564551840938d08bd279c8,

title = "Polypeptides with permease activity",

abstract = "The invention relates to a polypeptide having one or more substitution corresponding to F85T/A/C/H/M/N, T89H/D/C/A/N, V187T/C/D/E/F/G/H/K/M/Q/R/S/W/Y, A191N/G/P/ C/D/F/H/I/K/Q/V/W/Y, Y214V/Q/G/L/M/N/P/R/S, Q215L/M/I/A/C/D/F/S, I218K/N/A/C/D/E/H/L, T219G/F/D/N, I222D/C/H/E/G/P/S/V/Y, Y226D/M/R/C/G/H/I/L/P/Q/T/W, Q338C/E/F/D/G/I/P/R/S/T/V/W/Y, M339N/V/D/E/H/K/P/Q/R/Y, The invention relates to a polypeptide having one or more substitution corresponding to T89C/Y, V187M/Q/C/G/Y, A191 l/K/D/C/E/N/W/R/P, Y214L/P, Q215D/E/S/M/L/C/F/A, 1218W, T219V/L/R/E, I222G/Y/M/P/S/W, Y226M/T/P/Q, Q338R/I/D/E/F/G/P, M339Y/E/N, Q341V/Y/S/H, Q342N/H/R/C/F/G/I/K/L/P/S/T/W, L343Y/Q/I/C/E/K/N/P/S, N346G/I, N347S/L/K/G/TA/, Y350E/S/Q, G373R/K/L/IWY, N376K/Q/A/C/D/E/I/M/P, T380Y/G/M/A/S/D/E/I/K/L/W, S383Y/WA//C/E/I/L/Q/R, F446H/D/I, T448/R/K/H/D/E/W, T449F/H/A/G/I/L/P/QA/, T451W/Y/S, W455D/K/E/P/Q, N478Q/I/F/G, or W479S/I/F/D/E/H/M/N/R/T/Y of SEQ ID NO:59 wherein the polypeptide is member of the Major Facilitator Superfamily (MFS).",

author = "Paul Klaassen and {De Waal}, {Paulus Petrus} and {De Jong}, {Rene Marcel} and Driessen, {Arnold Jacob Mattieu} and Nijland, {Jeroen Gerben} and Shin, {Hyun Yong}",

year = "2014",

month = dec,

day = "11",

language = "English",

type = "Patent",

note = "WO2014195520",

}

TY - PAT

T1 - Polypeptides with permease activity

AU - Klaassen, Paul

AU - De Waal, Paulus Petrus

AU - De Jong, Rene Marcel

AU - Driessen, Arnold Jacob Mattieu

AU - Nijland, Jeroen Gerben

AU - Shin, Hyun Yong

PY - 2014/12/11

Y1 - 2014/12/11

N2 - The invention relates to a polypeptide having one or more substitution corresponding to F85T/A/C/H/M/N, T89H/D/C/A/N, V187T/C/D/E/F/G/H/K/M/Q/R/S/W/Y, A191N/G/P/ C/D/F/H/I/K/Q/V/W/Y, Y214V/Q/G/L/M/N/P/R/S, Q215L/M/I/A/C/D/F/S, I218K/N/A/C/D/E/H/L, T219G/F/D/N, I222D/C/H/E/G/P/S/V/Y, Y226D/M/R/C/G/H/I/L/P/Q/T/W, Q338C/E/F/D/G/I/P/R/S/T/V/W/Y, M339N/V/D/E/H/K/P/Q/R/Y, The invention relates to a polypeptide having one or more substitution corresponding to T89C/Y, V187M/Q/C/G/Y, A191 l/K/D/C/E/N/W/R/P, Y214L/P, Q215D/E/S/M/L/C/F/A, 1218W, T219V/L/R/E, I222G/Y/M/P/S/W, Y226M/T/P/Q, Q338R/I/D/E/F/G/P, M339Y/E/N, Q341V/Y/S/H, Q342N/H/R/C/F/G/I/K/L/P/S/T/W, L343Y/Q/I/C/E/K/N/P/S, N346G/I, N347S/L/K/G/TA/, Y350E/S/Q, G373R/K/L/IWY, N376K/Q/A/C/D/E/I/M/P, T380Y/G/M/A/S/D/E/I/K/L/W, S383Y/WA//C/E/I/L/Q/R, F446H/D/I, T448/R/K/H/D/E/W, T449F/H/A/G/I/L/P/QA/, T451W/Y/S, W455D/K/E/P/Q, N478Q/I/F/G, or W479S/I/F/D/E/H/M/N/R/T/Y of SEQ ID NO:59 wherein the polypeptide is member of the Major Facilitator Superfamily (MFS).

AB - The invention relates to a polypeptide having one or more substitution corresponding to F85T/A/C/H/M/N, T89H/D/C/A/N, V187T/C/D/E/F/G/H/K/M/Q/R/S/W/Y, A191N/G/P/ C/D/F/H/I/K/Q/V/W/Y, Y214V/Q/G/L/M/N/P/R/S, Q215L/M/I/A/C/D/F/S, I218K/N/A/C/D/E/H/L, T219G/F/D/N, I222D/C/H/E/G/P/S/V/Y, Y226D/M/R/C/G/H/I/L/P/Q/T/W, Q338C/E/F/D/G/I/P/R/S/T/V/W/Y, M339N/V/D/E/H/K/P/Q/R/Y, The invention relates to a polypeptide having one or more substitution corresponding to T89C/Y, V187M/Q/C/G/Y, A191 l/K/D/C/E/N/W/R/P, Y214L/P, Q215D/E/S/M/L/C/F/A, 1218W, T219V/L/R/E, I222G/Y/M/P/S/W, Y226M/T/P/Q, Q338R/I/D/E/F/G/P, M339Y/E/N, Q341V/Y/S/H, Q342N/H/R/C/F/G/I/K/L/P/S/T/W, L343Y/Q/I/C/E/K/N/P/S, N346G/I, N347S/L/K/G/TA/, Y350E/S/Q, G373R/K/L/IWY, N376K/Q/A/C/D/E/I/M/P, T380Y/G/M/A/S/D/E/I/K/L/W, S383Y/WA//C/E/I/L/Q/R, F446H/D/I, T448/R/K/H/D/E/W, T449F/H/A/G/I/L/P/QA/, T451W/Y/S, W455D/K/E/P/Q, N478Q/I/F/G, or W479S/I/F/D/E/H/M/N/R/T/Y of SEQ ID NO:59 wherein the polypeptide is member of the Major Facilitator Superfamily (MFS).

M3 - Patent

M1 - WO2014195520

ER -