Pre-Incubation and Low Temperatures in Quantitative Radioreceptor Assays

K. Ensing; R. A. de Zeeuw

doi:10.1080/00032718408065338

Pre-Incubation and Low Temperatures in Quantitative Radioreceptor Assays

K. Ensing^*
, R. A. de Zeeuw

^*Corresponding author voor dit werk

Onderzoeksoutput › Academic › peer review

10 Citaten (Scopus)

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The detection limits of drugs in quantitative RRA are primarily determined by their affinities towards the receptor. Yet, the concentration of radiolabeled ligand, necessary for quantification of receptor-bound drug, increases the theoretical detection limit. Therefore the influences of low temperatures and pre-incubation on the detection limit was studied.

Originele taal-2	English
Pagina's (van-tot)	1647-1658
Aantal pagina's	12
Tijdschrift	Analytical letters part b-Clinical and biochemical analysis
Volume	17
Nummer van het tijdschrift	14
DOI's	https://doi.org/10.1080/00032718408065338
Status	Published - 1984

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title = "Pre-Incubation and Low Temperatures in Quantitative Radioreceptor Assays",

abstract = "The detection limits of drugs in quantitative RRA are primarily determined by their affinities towards the receptor. Yet, the concentration of radiolabeled ligand, necessary for quantification of receptor-bound drug, increases the theoretical detection limit. Therefore the influences of low temperatures and pre-incubation on the detection limit was studied.",

author = "K. Ensing and \{de Zeeuw\}, \{R. A.\}",

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T1 - Pre-Incubation and Low Temperatures in Quantitative Radioreceptor Assays

AU - Ensing, K.

AU - de Zeeuw, R. A.

PY - 1984

Y1 - 1984

N2 - The detection limits of drugs in quantitative RRA are primarily determined by their affinities towards the receptor. Yet, the concentration of radiolabeled ligand, necessary for quantification of receptor-bound drug, increases the theoretical detection limit. Therefore the influences of low temperatures and pre-incubation on the detection limit was studied.

AB - The detection limits of drugs in quantitative RRA are primarily determined by their affinities towards the receptor. Yet, the concentration of radiolabeled ligand, necessary for quantification of receptor-bound drug, increases the theoretical detection limit. Therefore the influences of low temperatures and pre-incubation on the detection limit was studied.

U2 - 10.1080/00032718408065338

DO - 10.1080/00032718408065338

M3 - Article

SN - 0003-2719

VL - 17

SP - 1647

EP - 1658

JO - Analytical letters part b-Clinical and biochemical analysis

JF - Analytical letters part b-Clinical and biochemical analysis

IS - 14

ER -

Pre-Incubation and Low Temperatures in Quantitative Radioreceptor Assays

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