PROLONGED SURVIVAL OF SKIN-GRAFTS FOLLOWING TREATMENT WITH AN ANTIBODY TO A PUTATIVE CELL TRIGGERING MOLECULE, QCA-1

R ASPINALL*, J KAMPINGA, J VANDENBOGAERDE

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

1 Citaat (Scopus)

Samenvatting

The QCA-1 molecule (quiescent cell antigen-1) appears to be involved in the differentiation events undergone by T cell following occupancy of the antigen receptor. Here we show that modulation of the QCA-1 antigen from the surface of the cell normally follows activation, and that treatment of animals with the antibodies against the QCA-1 molecule inhibits the normal response to an allograft without appearing to alter the number of peripheral T cells or the expression by these cells of the alpha/beta T cell antigen receptor.

Originele taal-2English
Pagina's (van-tot)3053-3056
Aantal pagina's4
TijdschriftEuropean Journal of Immunology
Volume21
Nummer van het tijdschrift12
StatusPublished - dec-1991

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