TY - JOUR
T1 - Protein secretion in the Archaea
T2 - multiple paths towards a unique cell surface
AU - Albers, Sonja-Verena
AU - Szabo, Zalan
AU - Driessen, Arnold J. M.
PY - 2006/7
Y1 - 2006/7
N2 - Archaea are similar to other prokaryotes in most aspects of cell structure but are unique with respect to the lipid composition of the cytoplasmic membrane and the structure of the cell surface. Membranes of archaea are composed of glycerol-ether lipids instead of glycerol-ester lipids and are based on isoprenoid side chains, whereas the cell walls are formed by surface-layer proteins. The unique cell surface of archaea requires distinct solutions to the problem of how proteins cross this barrier to be either secreted into the medium or assembled as appendages at the cell surface.
AB - Archaea are similar to other prokaryotes in most aspects of cell structure but are unique with respect to the lipid composition of the cytoplasmic membrane and the structure of the cell surface. Membranes of archaea are composed of glycerol-ether lipids instead of glycerol-ester lipids and are based on isoprenoid side chains, whereas the cell walls are formed by surface-layer proteins. The unique cell surface of archaea requires distinct solutions to the problem of how proteins cross this barrier to be either secreted into the medium or assembled as appendages at the cell surface.
KW - SIGNAL-RECOGNITION PARTICLE
KW - ARGININE TRANSLOCATION PATHWAY
KW - GRAM-NEGATIVE BACTERIA
KW - HALOBACTERIUM SPECIES NRC-1
KW - SULFOLOBUS-SOLFATARICUS
KW - PSEUDOMONAS-AERUGINOSA
KW - HALOFERAX-VOLCANII
KW - ESCHERICHIA-COLI
KW - METHANOCOCCUS-VOLTAE
KW - CONDUCTING CHANNEL
U2 - 10.1038/nrmicro1440
DO - 10.1038/nrmicro1440
M3 - Review article
SN - 1740-1526
VL - 4
SP - 537
EP - 547
JO - Nature Reviews Microbiology
JF - Nature Reviews Microbiology
IS - 7
ER -