Proteinuria and progression of renal disease: Therapeutic implications

RT Gansevoort; GJ Navis; JH Wapstra; PE de Jong; D de Zeeuw

Proteinuria and progression of renal disease: Therapeutic implications

RT Gansevoort^*, GJ Navis, JH Wapstra, PE de Jong, D de Zeeuw

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The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.

Originele taal-2	English
Pagina's (van-tot)	133-140
Aantal pagina's	8
Tijdschrift	Current Opinion in Nephrology and Hypertension
Volume	6
Nummer van het tijdschrift	2
Status	Published - mrt.-1997

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@article{bcb58f8a5da6495085df752ba81aefe0,

title = "Proteinuria and progression of renal disease: Therapeutic implications",

abstract = "The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.",

keywords = "GLOMERULAR MESANGIAL CELLS, GLYCOSYLATION END-PRODUCTS, HUMAN DIABETIC NEPHROPATHY, BLOOD-PRESSURE CONTROL, OVERLOAD PROTEINURIA, GLYCATED ALBUMIN, EXPRESSION, RAT, METAANALYSIS, RESTRICTION",

author = "RT Gansevoort and GJ Navis and JH Wapstra and {de Jong}, PE and {de Zeeuw}, D",

year = "1997",

month = mar,

language = "English",

volume = "6",

pages = "133--140",

journal = "Current Opinion in Nephrology and Hypertension",

issn = "1062-4821",

publisher = "Lippincott Williams and Wilkins",

number = "2",

}

TY - JOUR

T1 - Proteinuria and progression of renal disease

T2 - Therapeutic implications

AU - Gansevoort, RT

AU - Navis, GJ

AU - Wapstra, JH

AU - de Jong, PE

AU - de Zeeuw, D

PY - 1997/3

Y1 - 1997/3

N2 - The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.

AB - The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.

KW - GLOMERULAR MESANGIAL CELLS

KW - GLYCOSYLATION END-PRODUCTS

KW - HUMAN DIABETIC NEPHROPATHY

KW - BLOOD-PRESSURE CONTROL

KW - OVERLOAD PROTEINURIA

KW - GLYCATED ALBUMIN

KW - EXPRESSION

KW - RAT

KW - METAANALYSIS

KW - RESTRICTION

M3 - Review article

SN - 1062-4821

VL - 6

SP - 133

EP - 140

JO - Current Opinion in Nephrology and Hypertension

JF - Current Opinion in Nephrology and Hypertension

IS - 2

ER -

Proteinuria and progression of renal disease: Therapeutic implications

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