TY - JOUR
T1 - Psychological Interventions for Children with Functional Somatic Symptoms
T2 - A Systematic Review and Meta-Analysis
AU - Bonvanie, Irma J
AU - Kallesøe, Karen H
AU - Janssens, Karin A M
AU - Schröder, Andreas
AU - Rosmalen, Judith G M
AU - Rask, Charlotte U
N1 - Copyright © 2017 Elsevier Inc. All rights reserved.
PY - 2017/8
Y1 - 2017/8
N2 - Objective: To analyze the effectiveness of psychological treatments on symptom load and associated disability in children with functional somatic symptoms, and to explore potential moderators of effects.Study design: Cochrane, PubMed, PsycINFO, EMBASE, and CINAHL were searched for randomized controlled trials published in peer-reviewed journals. Randomized controlled trials studying the effect of a psychological treatment on symptom load and disability in children with functional somatic symptoms were selected. Data on symptom load, disability, and school absence directly post-treatment and at follow-up were extracted by 2 assessors. Studies were appraised with the Cochrane risk of bias tool. Standardized mean differences were pooled in a random-effects model. Heterogeneity in effect-sizes was explored by use of meta-regressions. PROSPERO Registration ID: CRD42015029667.Results: Out of 4098 identified records, 27 studies were included in this review of which 21 were included in meta-analyses. Psychological treatments reduced symptom load (Hedges g = -0.61), disability (Hedges g = -0.42), and school absence (Hedges g = -0.51) post-treatment in children suffering from various functional somatic symptoms. Effects were maintained at follow-up. Type and duration of symptoms, age, and treatment dose did not explain heterogeneity in effect-sizes between studies. Effect-sizes should be interpreted with caution because of the variety in outcome measures, unexplained heterogeneity in found effects and potential publication bias.Conclusions: Psychological interventions reduce symptom load, disability, and school absence in children with functional somatic symptoms. Future research should clarify which patient and treatment characteristics modify outcomes.
AB - Objective: To analyze the effectiveness of psychological treatments on symptom load and associated disability in children with functional somatic symptoms, and to explore potential moderators of effects.Study design: Cochrane, PubMed, PsycINFO, EMBASE, and CINAHL were searched for randomized controlled trials published in peer-reviewed journals. Randomized controlled trials studying the effect of a psychological treatment on symptom load and disability in children with functional somatic symptoms were selected. Data on symptom load, disability, and school absence directly post-treatment and at follow-up were extracted by 2 assessors. Studies were appraised with the Cochrane risk of bias tool. Standardized mean differences were pooled in a random-effects model. Heterogeneity in effect-sizes was explored by use of meta-regressions. PROSPERO Registration ID: CRD42015029667.Results: Out of 4098 identified records, 27 studies were included in this review of which 21 were included in meta-analyses. Psychological treatments reduced symptom load (Hedges g = -0.61), disability (Hedges g = -0.42), and school absence (Hedges g = -0.51) post-treatment in children suffering from various functional somatic symptoms. Effects were maintained at follow-up. Type and duration of symptoms, age, and treatment dose did not explain heterogeneity in effect-sizes between studies. Effect-sizes should be interpreted with caution because of the variety in outcome measures, unexplained heterogeneity in found effects and potential publication bias.Conclusions: Psychological interventions reduce symptom load, disability, and school absence in children with functional somatic symptoms. Future research should clarify which patient and treatment characteristics modify outcomes.
KW - CHRONIC-FATIGUE-SYNDROME
KW - RANDOMIZED CONTROLLED-TRIAL
KW - RECURRENT ABDOMINAL-PAIN
KW - COGNITIVE-BEHAVIORAL THERAPY
KW - IRRITABLE-BOWEL-SYNDROME
KW - TERM-FOLLOW-UP
KW - EMPIRICALLY SUPPORTED TREATMENTS
KW - GUT-DIRECTED HYPNOTHERAPY
KW - TENSION-TYPE HEADACHE
KW - SOMATIZATION INVENTORY
U2 - 10.1016/j.jpeds.2017.03.017
DO - 10.1016/j.jpeds.2017.03.017
M3 - Review article
C2 - 28416243
SN - 0022-3476
VL - 187
SP - 272-281.e17
JO - The Journal of Pediatrics
JF - The Journal of Pediatrics
ER -