Quantitative analysis of organelle abundance, morphology and dynamics

Tim van Zutphen, Ida J. van der Klei*

*Bijbehorende auteur voor dit werk

Onderzoeksoutputpeer review

10 Citaten (Scopus)
687 Downloads (Pure)

Samenvatting

Recent data indicate that morphological characteristics of cell organelles are important for their function in the cell. These characteristics include not only their shape, number and size, but also their distribution in the cell. Moreover, the dynamics of processes that result in changes in these characteristics (e.g. organelle fission, fusion, autophagy, transport) influence the function of the cell.

For a better understanding of these processes quantitative approaches are important. Here we give an overview of contemporary biochemical and microscopy methods that are used to quantify organelle abundance, morphology and the kinetics of the processes that cause changes in these properties.

Originele taal-2English
Pagina's (van-tot)127-132
Aantal pagina's6
TijdschriftCurrent Opinion in Biotechnology
Volume22
Nummer van het tijdschrift1
DOI's
StatusPublished - feb.-2011

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