Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

TJ Postma; M Klein; CCP Verstappen; JEC Bromberg; M Swennen; JA Langendijk; MJB Taphoorn; P Scheltens; BJ Slotman; HM van der Ploeg; NK Aaronson; JJ Heimans

doi:10.1212/WNL.59.1.121

Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

TJ Postma^*, M Klein, CCP Verstappen, JEC Bromberg, M Swennen, JA Langendijk, MJB Taphoorn, P Scheltens, BJ Slotman, HM van der Ploeg, NK Aaronson, JJ Heimans

^*Corresponding author voor dit werk

Onderzoeksoutput: Article › Academic › peer review

82 Citaten (Scopus)

Samenvatting

Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

Originele taal-2	English
Pagina's (van-tot)	121-123
Aantal pagina's	3
Tijdschrift	Neurology
Volume	59
Nummer van het tijdschrift	1
DOI's	https://doi.org/10.1212/WNL.59.1.121
Status	Published - 9-jul.-2002

Toegang tot document

10.1212/WNL.59.1.121

Handle.net

Permanente koppeling

Citeer dit

@article{c55a8e6043eb411daa2ea6c5b8608fdd,

title = "Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma",

abstract = "Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.",

keywords = "MRI, CT",

author = "TJ Postma and M Klein and CCP Verstappen and JEC Bromberg and M Swennen and JA Langendijk and MJB Taphoorn and P Scheltens and BJ Slotman and {van der Ploeg}, HM and NK Aaronson and JJ Heimans",

year = "2002",

month = jul,

day = "9",

doi = "10.1212/WNL.59.1.121",

language = "English",

volume = "59",

pages = "121--123",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

number = "1",

}

TY - JOUR

T1 - Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

AU - Postma, TJ

AU - Klein, M

AU - Verstappen, CCP

AU - Bromberg, JEC

AU - Swennen, M

AU - Langendijk, JA

AU - Taphoorn, MJB

AU - Scheltens, P

AU - Slotman, BJ

AU - van der Ploeg, HM

AU - Aaronson, NK

AU - Heimans, JJ

PY - 2002/7/9

Y1 - 2002/7/9

N2 - Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

AB - Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

KW - MRI

KW - CT

U2 - 10.1212/WNL.59.1.121

DO - 10.1212/WNL.59.1.121

M3 - Article

SN - 0028-3878

VL - 59

SP - 121

EP - 123

JO - Neurology

JF - Neurology

IS - 1

ER -

Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

Samenvatting

Toegang tot document

Handle.net

Vingerafdruk

Citeer dit