Rats exposed to maternal depression and antidepressant treatment during development show sex differences in social behavior

D. J. Houwing, A. S. Ramsteijn, L. Staal, J.M. Swart, J. D. A. Olivier

Onderzoeksoutput: PosterAcademic


Major depression occurs in about 7 percent of pregnant women, making antidepressant treatment often necessary. Depressive symptoms during pregnancy can negatively influence the developing child, while antidepressants affect the behavioral development and health of the child as well [1]. For example, taking selective serotonin reuptake inhibitors (SSRIs) during pregnancy increases the risk of having a child that will develop a social disorder such as autism spectrum disorder [ASD; 2]. In humans, it is difficult to dissociate the effects of the depression itself from the effects of the antidepressant, making it unclear whether the exposed fetus is at increased risk. Therefore, we investigated the effects of maternal depression, antidepressant treatment, and their combination during pregnancy on social behavior in rat offspring.
Originele taal-2English
Aantal pagina's2
StatusPublished - 3-sep.-2017
Evenement30th Congress of the European College of Neuropsychopharmacology (ECNP) - Paris, France
Duur: 2-sep.-20175-sep.-2017
Congresnummer: 30


Conference30th Congress of the European College of Neuropsychopharmacology (ECNP)
Verkorte titelECNP 2017
Internet adres

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