Real-life assessment of chronic rhinosinusitis patients using mobile technology: The mySinusitisCoach project by EUFOREA

Sven F. Seys*, Shana De Bont, Wytske J. Fokkens, Claus Bachert, Isam Alobid, Manuel Bernal-Sprekelsen, Leif Bjermer, Ina Callebaut, Lars-Olaf Cardell, Sean Carrie, Paolo Castelnuovo, Russell Cathcart, Jannis Constantinidis, Leen Cools, Marjolein Cornet, Gregory Clement, Tony Cox, Lieve Delsupehe, Jaime Correia-de-Sousa, Lauren DeneyerGeert De Vos, Zuzana Diamant, Maria Doulaptsi, Simon Gane, Philippe Gevaert, Claire Hopkins, Valerie Hox, Thomas Hummel, Werner Hosemann, Raf Jacobs, Mark Jorissen, Anette Kjeldsen, Basile N. Landis, Winde Lemmens, Andreas Leunig, Valerie Lund, Gert Marien, Joaquim Mullol, Metin Onerci, Susanna Palkonen, Isabel Proano, Emmanuel Prokopakis, Dermot Ryan, Herbert Riechelmann, Pernilla Sahlstrand-Johnson, Sanna Salmi-Toppila, Christine Segboer, Kato Speleman, Andreas Steinsvik, Pavol Surda

*Bijbehorende auteur voor dit werk

    OnderzoeksoutputAcademicpeer review

    21 Citaten (Scopus)
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    Background Chronic rhinosinusitis (CRS) is a chronic inflammatory disease associated with a substantial personal and socioeconomic burden. Monitoring of patient-reported outcomes by mobile technology offers the possibility to better understand real-life burden of CRS. Methods This study reports on the cross-sectional evaluation of data of 626 users of mySinusitisCoach (mSC), a mobile application for CRS patients. Patient characteristics of mSC users were analysed as well as the level of disease control based on VAS global rhinosinusitis symptom score and adapted EPOS criteria. Results The mSC cohort represents a heterogeneous group of CRS patients with a diverse pattern of major symptoms. Approximately half of patients reported nasal polyps. 47.3% of all CRS patients were uncontrolled based on evaluation of VAS global rhinosinusitis symptom score compared to 40.9% based on adapted EPOS criteria. The impact of CRS on sleep quality and daily life activities was significantly higher in uncontrolled versus well-controlled patients. Half of patients had a history of FESS (functional endoscopic sinus surgery) and reported lower symptom severity compared to patients without a history of FESS, except for patients with a history of more than 3 procedures. Patients with a history of FESS reported higher VAS levels for impaired smell. Conclusion Real-life data confirm the high disease burden in uncontrolled CRS patients, clearly impacting quality of life. Sinus surgery improves patient-reported outcomes, but not in patients with a history of more than 3 procedures. Mobile technology opens a new era of real-life monitoring, supporting the evolution of care towards precision medicine.

    Originele taal-2English
    Pagina's (van-tot)2867-2878
    Aantal pagina's12
    Nummer van het tijdschrift11
    StatusPublished - nov.-2020

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