Red Blood Cell Transfusions Affect Intestinal and Cerebral Oxygenation Differently in Preterm Infants with and without Subsequent Necrotizing Enterocolitis

Willemien S. Kalteren*, Sara J. Kuik, Koenraad N. J. A. Van Braeckel, Jan B. F. Hulscher, Arend F. Bos, Elisabeth M. W. Kooi, Michelle E. van der Laan

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

8 Citaten (Scopus)


Objective To assess intestinal and cerebral oxygenation during and after red blood cell (RBC) transfusions in preterms with or without subsequent transfusion-associated necrotizing enterocolitis (TANEC).

Study Design In preterms of

Results In TANEC infants, r (c) SO (2) was lower during and after RBC transfusions than in controls, median (interquartile range) 55% (50-62) versus 72% (65-75), p

Conclusion In preterm infants lower r (c) SO (2) , but not r (int) SO (2) , values during and after RBC transfusions are associated with TANEC. Lower r (int) SO (2) and r (c) SO (2) variabilities after RBC transfusions may represent a diminished capacity for vascular adaptation, possibly leading to TANEC.

Originele taal-2English
Pagina's (van-tot)1031-1037
Aantal pagina's7
TijdschriftAmerican Journal of Perinatology
Nummer van het tijdschrift11
StatusPublished - sep-2018

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