Respiratory muscle activity and dyspnea during exercise in chronic obstructive pulmonary disease

M. L. Duiverman*, E. W. J. de Boer, L. A. van Eykern, M. H. G. de Greef, D. F. Jansen, J. B. Wempe, H. A. M. Kerstjens, P. J. Wijkstra

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

27 Citaten (Scopus)


We aimed to determine by non-invasive EMG, whether during exercise: (1)COPD patients increase scalene and intercostal EMG activity, (2) increased EMG activity is associated with increased dyspnea, and (3) the ratio between EMG activity and volume displacement is increased in COPD compared to healthy subjects (HS).

During a maximal incremental cycle test, scalene and intercostal EMG was derived transcutaneously in 17 COPD patients and 10 HS. Dyspnea was quantified using a Borg scale, ranging from zero to 10 (maximal dyspnea). For analyses the ratio between inspiratory muscle activity during exercise and activity during quiet breathing was used (logEMGAR).

In COPD patients, scalene and intercostal activity increased at greater rate early in exercise compared to that of the HS. With a doubling of the logEMGAR, in COPD, dyspnea increased with 2.8/3.8 points, while in the HS, dyspnea increased less with 1.1/1.4 points. In COPD, there was a larger increase in EMG activity relatively to tidal volume increases. (C) 2009 Elsevier B.V. All rights reserved.

Originele taal-2English
Pagina's (van-tot)195-200
Aantal pagina's6
TijdschriftRespiratory physiology & neurobiology
Nummer van het tijdschrift2
StatusPublished - 30-jun.-2009

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