Samenvatting
A novel and versatile design of DNA-lipid conjugates is presented. The assembly of the DNA headgroups into G-quadruplex structures is essential for the formation of micelles and their stability. By hybridization with a complementary oligonucleotide the micelles were destabilized, resulting in cargo release. In combination with a hairpin DNA aptamer as complementary strand, the release is obtained selectively by the presence of ATP.
Originele taal-2 | English |
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Pagina's (van-tot) | 260-263 |
Aantal pagina's | 4 |
Tijdschrift | Chemical communications (Cambridge, England) |
Volume | 54 |
Vroegere onlinedatum | 6-dec.-2017 |
DOI's | |
Status | Published - 11-jan.-2018 |