Saccharide-Containing Dynamic Proteoids

Yun Liu; Marc C. A. Stuart; Martin D. Witte; Eric Buhler; Anna Katharina Herta Hirsch

doi:10.1002/chem.201703584

Saccharide-Containing Dynamic Proteoids

Yun Liu, Marc C. A. Stuart, Martin D. Witte, Eric Buhler^*, Anna Katharina Herta Hirsch^*

^*Bijbehorende auteur voor dit werk

Onderzoeksoutput › Academic › peer review

4 Citaten (Scopus)

190 Downloads (Pure)

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Dynamic proteoids are dynamic covalent analogues of proteins which can be used as novel adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dialdehyde, the biocompatibility of biodynamers should be enhanced compared to previously reported biodynamers.

Originele taal-2	English
Pagina's (van-tot)	16162-16166
Aantal pagina's	5
Tijdschrift	Chemistry
Volume	23
Nummer van het tijdschrift	64
DOI's	https://doi.org/10.1002/chem.201703584
Status	Published - 16-nov.-2017

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10.1002/chem.201703584Licentie: CC BY-NC

Saccharide‐Containing Dynamic ProteoidsFinal publisher's version, 388 KBLicentie: CC BY-NC

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title = "Saccharide-Containing Dynamic Proteoids",

abstract = "Dynamic proteoids are dynamic covalent analogues of proteins which can be used as novel adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dialdehyde, the biocompatibility of biodynamers should be enhanced compared to previously reported biodynamers.",

keywords = "Journal Article, MOLECULES, SEQUENCE, COVALENT CHEMISTRY, POLYMERS, ANALOGS, GLYCODYNAMERS, OLIGOSACCHARIDES, GENERATION",

author = "Yun Liu and Stuart, {Marc C. A.} and Witte, {Martin D.} and Eric Buhler and Hirsch, {Anna Katharina Herta}",

note = "{\textcopyright} 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",

year = "2017",

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doi = "10.1002/chem.201703584",

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T1 - Saccharide-Containing Dynamic Proteoids

AU - Liu, Yun

AU - Stuart, Marc C. A.

AU - Witte, Martin D.

AU - Buhler, Eric

AU - Hirsch, Anna Katharina Herta

PY - 2017/11/16

Y1 - 2017/11/16

N2 - Dynamic proteoids are dynamic covalent analogues of proteins which can be used as novel adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dialdehyde, the biocompatibility of biodynamers should be enhanced compared to previously reported biodynamers.

AB - Dynamic proteoids are dynamic covalent analogues of proteins which can be used as novel adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dialdehyde, the biocompatibility of biodynamers should be enhanced compared to previously reported biodynamers.

KW - Journal Article

KW - MOLECULES

KW - SEQUENCE

KW - COVALENT CHEMISTRY

KW - POLYMERS

KW - ANALOGS

KW - GLYCODYNAMERS

KW - OLIGOSACCHARIDES

KW - GENERATION

U2 - 10.1002/chem.201703584

DO - 10.1002/chem.201703584

M3 - Article

C2 - 28981987

VL - 23

SP - 16162

EP - 16166

JO - Chemistry

JF - Chemistry

SN - 0947-6539

IS - 64

ER -