Samenvatting
The work described in this thesis focused on two main points. Firstly, we aimed to unravel the effect of radiation-induced microenvironmental changes on the regenerative potential of SGSCs and investigate the possible modulation or intervention of microenvironmental factors to improve SGSC function by using salivary gland organoids as a model. Secondly, we utilized human salivary gland biopsy-derived organoids to explore the SARS-CoV-2 infection process.
Originele taal-2 | English |
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Kwalificatie | Doctor of Philosophy |
Toekennende instantie |
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Begeleider(s)/adviseur |
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Datum van toekenning | 26-sep.-2022 |
Plaats van publicatie | [Groningen] |
Uitgever | |
DOI's | |
Status | Published - 2022 |