Salivary gland organoids to study radiation-induced microenvironmental changes: a versatile translational tool

Yi Wu

    Onderzoeksoutput

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    Samenvatting

    The work described in this thesis focused on two main points. Firstly, we aimed to unravel the effect of radiation-induced microenvironmental changes on the regenerative potential of SGSCs and investigate the possible modulation or intervention of microenvironmental factors to improve SGSC function by using salivary gland organoids as a model. Secondly, we utilized human salivary gland biopsy-derived organoids to explore the SARS-CoV-2 infection process.
    Originele taal-2English
    KwalificatieDoctor of Philosophy
    Toekennende instantie
    • Rijksuniversiteit Groningen
    Begeleider(s)/adviseur
    • Coppes, Rob, Supervisor
    • Vissink, Arjan, Supervisor
    • Barazzuol, Lara, Co-supervisor
    • Pringle, Sarah, Co-supervisor
    Datum van toekenning26-sep.-2022
    Plaats van publicatie[Groningen]
    Uitgever
    DOI's
    StatusPublished - 2022

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