TY - JOUR
T1 - Sex differences in cardiomyopathies
AU - Meyer, Sven
AU - van der Meer, Peter
AU - van Tintelen, J. Peter
AU - van den Berg, Maarten P.
N1 - © 2014 The Authors. European Journal of Heart Failure © 2014 European Society of Cardiology.
PY - 2014/3
Y1 - 2014/3
N2 - Cardiomyopathies are a heterogeneous group of heart muscle diseases with a variety of specific phenotypes. According to the contemporary European Society of Cardiology classification, they are classified into hypertrophic (HCM), dilated (DCM), arrhythmogenic right ventricular (ARVC), restrictive (RCM), and unclassified cardiomyopathies. Each class is aetiologically further categorized into inherited (familial) and non-inherited (non-familial) forms. There is substantial evidence that biological sex is a strong modulator of the clinical manifestation of these cardiomyopathies, and sex-specific characteristics are detectable in all classes. For the clinician, it is important to know the sex-specific aspects of clinical disease expression and the potential modes of inheritance or the hereditary influences underlying the development of cardiomyopathies, since these may aid in diagnosing such diseases in both sexes.
AB - Cardiomyopathies are a heterogeneous group of heart muscle diseases with a variety of specific phenotypes. According to the contemporary European Society of Cardiology classification, they are classified into hypertrophic (HCM), dilated (DCM), arrhythmogenic right ventricular (ARVC), restrictive (RCM), and unclassified cardiomyopathies. Each class is aetiologically further categorized into inherited (familial) and non-inherited (non-familial) forms. There is substantial evidence that biological sex is a strong modulator of the clinical manifestation of these cardiomyopathies, and sex-specific characteristics are detectable in all classes. For the clinician, it is important to know the sex-specific aspects of clinical disease expression and the potential modes of inheritance or the hereditary influences underlying the development of cardiomyopathies, since these may aid in diagnosing such diseases in both sexes.
KW - Sex difference
KW - Cardiomyopathies
KW - Sex
KW - RIGHT-VENTRICULAR CARDIOMYOPATHY
KW - GENDER-RELATED DIFFERENCES
KW - TERM-FOLLOW-UP
KW - FAMILIAL DILATED CARDIOMYOPATHY
KW - BIOPSY-PROVEN MYOCARDITIS
KW - BECKER MUSCULAR-DYSTROPHY
KW - X-CHROMOSOME INACTIVATION
KW - CARDIOLOGY WORKING GROUP
KW - SOCIETY-OF-CARDIOLOGY
KW - HYPERTROPHIC CARDIOMYOPATHY
U2 - 10.1002/ejhf.15
DO - 10.1002/ejhf.15
M3 - Review article
C2 - 24464619
SN - 1388-9842
VL - 16
SP - 238
EP - 247
JO - European Journal of Heart Failure
JF - European Journal of Heart Failure
IS - 3
ER -