Shaping membranes into autophagosomes

Muriel Mari, Fulvio Reggiori*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

10 Citaten (Scopus)


The class III phosphatidylinositol 3-kinase( Pi( 3) KC3) is part of a key complex regulating autophagy. How this complex mechanistically contributes to autophagosome formation remains largely unknown. The BaR-domain- containing protein Bif-1/ endophilin B1, commonly associated with the control of membrane curvature, has been identified as a new interacting partner for Pi( 3) KC3, suggesting the complex plays an active part in the regulation of membrane dynamics during autophagy.

Originele taal-2English
Pagina's (van-tot)1125-1127
Aantal pagina's3
TijdschriftNature Cell Biology
Nummer van het tijdschrift10
StatusPublished - okt-2007

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