Short and Long Term Mortality Rates after a Lower Limb Amputation

L. V. Fortington*, J. H. B. Geertzen, J. J. van Netten, K. Postema, G. M. Rommers, P. U. Dijkstra

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

154 Citaten (Scopus)
889 Downloads (Pure)

Samenvatting

Objective: To determine mortality rates after a first lower limb amputation and explore the rates for different subpopulations.

Methods: Retrospective cohort study of all people who underwent a first amputation at or proximal to transtibial level, in an area of 1.7 million people. Analysis with Kaplan-Meier curves and Log Rank tests for univariate associations of psycho-social and health variables. Logistic regression for odds of death at 30-days, 1-year and 5-years.

Results: 299 people were included. Median time to death was 20.3 months (95%CI: 13.1; 27.5). 30-day mortality = 22%; odds of death 2.3 times higher in people with history of cerebrovascular disease (95%CI: 1.2; 4.7, P = 0.016). 1 year mortality = 44%; odds of death 3.5 times higher for people with renal disease (95%CI: 1.8; 7.0, P <0.001). 5-years mortality = 77%; odds of death 5.4 times higher for people with renal disease (95%CI: 1.8; 16.0,P = 0.003). Variation in mortality rates was most apparent in different age groups; people 75-84 years having better short term outcomes than those younger and older.

Conclusions: Mortality rates demonstrated the frailty of this population, with almost one quarter of people dying within 30-days, and almost half at 1 year. People with cerebrovascular had higher odds of death at 30 days, and those with renal disease and 1 and 5 years, respectively. (C) 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

Originele taal-2English
Pagina's (van-tot)124-131
Aantal pagina's8
TijdschriftEuropean Journal of Vascular and Endovascular Surgery
Volume46
Nummer van het tijdschrift1
DOI's
StatusPublished - jul-2013

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