Simulating realistic membrane shapes

Weria Pezeshkian, Siewert J. Marrink*

*Bijbehorende auteur voor dit werk

Onderzoeksoutputpeer review

Samenvatting

Biological membranes exhibit diversity in their shapes and complexity in chemical compositions that are linked to many cellular functions. These two central features of biomembranes have been the subject of numerous simulation studies, using a diverse range of computational techniques. Currently, the field is able to capture this complexity at increasing levels of realism and connect the microscopic view on protein-lipid interactions to cellular morphologies at the level of entire organelles. Here we highlight recent advances in this topic, identify current bottlenecks, and sketch possible ways ahead.

Originele taal-2English
Artikelnummerj.ceb.2021.02.009
Pagina's (van-tot)103-111
Aantal pagina's9
TijdschriftCurrent Opinion in Cell Biology
Volume71
Vroegere onlinedatum12-mrt-2021
DOI's
StatusE-pub ahead of print - 12-mrt-2021

Citeer dit