Single-Particle Cryo-EM of Membrane Proteins in Lipid Nanodiscs

Valeria Kalienkova, Carolina Alvadia, Vanessa Clerico Mosina, Cristina Paulino*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

4 Citaten (Scopus)


Single-particle cryo-electron microscopy has become an indispensable technique in structural biology. In particular when studying membrane proteins, it allows the use of membrane-mimicking tools, which can be crucial for a comprehensive understanding of the structure-function relationship of the protein in its native environment. In this chapter we focus on the application of nanodiscs and use our recent studies on the TMEM16 family as an example.

Originele taal-2English
TitelExpression, Purification, and Structural Biology of Membrane Proteins
RedacteurenCamilo Perez, Timm Maier
Plaats van productie New York
UitgeverijHumana, New York, NY
Aantal pagina's29
ISBN van elektronische versie978-1-0716-0373-4
ISBN van geprinte versie978-1-0716-0372-7
StatusPublished - 2020

Publicatie series

NaamMethods in Molecular Biology
ISSN van geprinte versie1064-3745

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