SpotXplore: A Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks

Michel A. Westenberg*, Jos B. T. M. Roerdink, Oscar P. Kuipers, Sacha A. F. T. van Hijum

*Corresponding author voor dit werk

OnderzoeksoutputAcademicpeer review

7 Citaten (Scopus)
130 Downloads (Pure)

Samenvatting

SpotXplore is a plugin for Cytoscape for extraction and visualization of differentially expressed subnetworks (hotspots) from gene networks. The hotspot-based visualization approach enables interactive exploration of regulatory interactions in differentially expressed gene sets, and it allows a researcher to explore gene expression in direct relation to the affected cellular gene network. The hotspots provide a view beyond the commonly used metabolic pathways and gene ontologies.

Originele taal-2English
Pagina's (van-tot)2922-2923
Aantal pagina's2
TijdschriftBioinformatics
Volume26
Nummer van het tijdschrift22
DOI's
StatusPublished - nov.-2010

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