Enzymatic digestion is a key process in the gastrointestinal tract that we recreated in an earlier miniaturized system. In order to avoid the need to continuously supply digestive enzymes, this work studied the immobilization of digestive enzymes in a microsystem. Flow-through reactors were produced by stereolithography and the digestive enzyme, alpha-amylase, was immobilized onto the channel walls. The activity of immobilized alpha-amylase was determined by digestion of starch, with potential applications in organs-on-a-chip or other enzymatic conversions.
|Status||Published - 13-okt-2021|
|Evenement||25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021): MicroTAS 2021 - Palm Springs, United States|
Duur: 10-okt-2021 → 14-okt-2021
|Conference||25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021)|
|Verkorte titel||µTAS 2021|
|Periode||10/10/2021 → 14/10/2021|