Stereolithographic fabrication and characterization of immobilized enzyme reactors for in vitro digestions

OnderzoeksoutputAcademic

Samenvatting

Enzymatic digestion is a key process in the gastrointestinal tract that we recreated in an earlier miniaturized system. In order to avoid the need to continuously supply digestive enzymes, this work studied the immobilization of digestive enzymes in a microsystem. Flow-through reactors were produced by stereolithography and the digestive enzyme, alpha-amylase, was immobilized onto the channel walls. The activity of immobilized alpha-amylase was determined by digestion of starch, with potential applications in organs-on-a-chip or other enzymatic conversions.
Originele taal-2English
Pagina's1169
Aantal pagina's2
StatusPublished - 13-okt-2021
Evenement25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021): MicroTAS 2021 - Palm Springs, United States
Duur: 10-okt-202114-okt-2021
Congresnummer: 25
http://microtas2021.org

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021)
Verkorte titelµTAS 2021
Land/RegioUnited States
StadPalm Springs
Periode10/10/202114/10/2021
Internet adres

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