Structural Study of the Candida auris Ribosome

A. A. Atamas*, A. I. Guskov, A. V. Rogachev

*Corresponding author voor dit werk

OnderzoeksoutputAcademicpeer review

1 Citaat (Scopus)
27 Downloads (Pure)

Samenvatting

Abstract: Candida auris is a pathogenic fungus that causes infections in people with weakened immune systems. It is resistant to antimicrobial drugs, which complicates treatment. C. auris poses a serious threat to public health since it has high resistance and contagiousness. The ribosome plays an important role in the survival and development of this infection, and the search for inhibitors of the C. auris ribosome is of great importance. The authors used cryoelectron microscopy and single particle analysis to obtain the three-dimensional structure of the C. auris ribosome. Herein is described the architecture of the ribosome subunits and their interactions, providing valuable information for the development of novel antifungals against C. auris.

Originele taal-2English
Pagina's (van-tot)S56-S58
Aantal pagina's3
TijdschriftMoscow University Biological Sciences Bulletin
Volume78
Nummer van het tijdschriftSuppl 1
DOI's
StatusPublished - dec.-2023

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