Samenvatting

Therapeutic drug monitoring (TDM) results for ganciclovir in 12 different treatment episodes showed large intraindividual and interindividual variabilities in the trough concentration and area under the 24-hour concentration-time curve (AUC24). Despite adequate valganciclovir dosing, subtherapeutic concentrations were found in 30% of the treatment episodes. A decrease in viral load was observed regardless of subtherapeutic exposure. These findings show the need for target concentration evaluation and assessment of the applicability of ganciclovir TDM in children.

Originele taal-2English
Pagina's (van-tot)269-272
Aantal pagina's4
TijdschriftTherapeutic Drug Monitoring
Volume45
Nummer van het tijdschrift2
DOI's
StatusPublished - apr.-2023

Vingerafdruk

Duik in de onderzoeksthema's van 'Subtherapeutic Exposure of Ganciclovir in Children Despite Appropriate Dosing: A Short Communication'. Samen vormen ze een unieke vingerafdruk.

Citeer dit