Surgical management and autologous intestinal reconstruction in short bowel syndrome

Matthijs J. Hommel, Robertine van Baren, Jan Willem Haveman*

*Bijbehorende auteur voor dit werk

    OnderzoeksoutputAcademicpeer review

    19 Citaten (Scopus)


    Short bowel syndrome (SBS) is a serious condition with considerable morbidity and mortality. When treatment with parenteral nutrition fails and life-threatening complications occur, autologous intestinal reconstruction (AIR) should be considered before intestinal transplantation (ITx). Single or combined ITx should be reserved for patients with severe liver disease and as last resort in the treatment of SBS. Longitudinal intestinal lengthening and tailoring (LILT) has proven its value in AIR, but its availability depends on the expertise of the surgeons. Serial transverse enteroplasty (STEP) has similar success rates as LILT and fewer patients progress to ITx. STEP is also applicable at small bowel dilatation in ultra-short bowel syndrome. The scope may be widened when duodenal dilatation can be treated as well. Spiral intestinal lengthening and tailoring (SILT) is a promising alternative. More research is needed to confirm these findings. Therefore we suggest an international data registry for all intestinal lengthening procedures. (C) 2016 Elsevier Ltd. All rights reserved.

    Originele taal-2English
    Pagina's (van-tot)263-280
    Aantal pagina's18
    TijdschriftBest practice & research in clinical gastroenterology
    Nummer van het tijdschrift2
    StatusPublished - apr-2016

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