Symptomatic and asymptomatic airway hyperresponsiveness: epidemiological and pathological studies

In this thesis, we described the relationship of various allergy markers and the development of pulmonary function with the single or coinciding presence of respiratory syptoms and airway hyperresponsiveness (AHR) in a general adult population. Further, we investigated whether differences in inflammatory cells exist in the airways of subjects with and without respiratory symptoms and AHR. Further, factors associated with airway hyperresponsiveness (AHR) and possible mechanisms of AHR are discussed. ... Zie: Summary.