The biomechanical outcome after total hip replacement: Quantitative biomechanical evaluation of Computer-Assisted Femur First THR

Tim Weber


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    Sub-optimal implant positioning is one of the leading causes for implant failure in Total Hip Replacement (THR). Computer-assisted surgery in combination with ‘femur first’ (CAS FF) is believed to improve implant positioning and post-operative hip biomechanics. Combining patient-specific anatomy with patient-specific motion allows the computation of patient-specific biomechanics by means of musculoskeletal models (MM). This work applies MM to investigate operation-dependent differences between conventional THR and CAS FF in terms of biomechanics also focusing on MIS-approaches.
    A computational study showed that MIS approaches are superior to conventional approaches in terms of biomechanics. A prospective randomized controlled trial showed that CAS FF leads to a significantly improved hip reaction force (hrf) orientation compared to conventional THR. A trend for improved gait post-operatively for the CAS FF group did not reach statistical significance. The Improved hrf symmetry of the CAS FF group indicates a possible long-term benefit.
    Biomechanical load-cases as quantified by MM are an integral measure of patient-specific motion and anatomy and therefore able to provide a more complete picture of patients or populations in terms of biomechanics. The improved hrf orientation shows that the concept of combined anteversion leads to a favorable load-case scenario at an early stage.
    Originele taal-2English
    KwalificatieDoctor of Philosophy
    Toekennende instantie
    • Rijksuniversiteit Groningen
    • Verkerke, Bart, Supervisor
    • Bulstra, Sjoerd, Supervisor
    • Dendorfer, Sebastian, Supervisor, Externe Persoon
    • Renkawitz, Tobias, Co-supervisor, Externe Persoon
    Datum van toekenning17-jun-2015
    Plaats van publicatie[Groningen]
    Gedrukte ISBN's978-90-367-7976-0
    Elektronische ISBN's978-90-367-7975-3
    StatusPublished - 2015

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