The effect of treatment with bisoprolol-first versus enalapril-first on cardiac structure and function in heart failure

Louis L. M. Van de Ven; Dirk J. van Veldhuisen; Michael Goulder; Zsolt Zilahi; Wilfried R. Meyer; Ronnie Willenheimer

doi:10.1016/j.ijcard.2009.04.040

The effect of treatment with bisoprolol-first versus enalapril-first on cardiac structure and function in heart failure

Louis L. M. Van de Ven, Dirk J. van Veldhuisen, Michael Goulder, Zsolt Zilahi, Wilfried R. Meyer, Ronnie Willenheimer^*

^*Corresponding author voor dit werk

Cardiovasculair Centrum

Onderzoeksoutput › Academic › peer review

10 Citaten (Scopus)

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Background: In CIBIS III, initiating chronic heart failure (CHF) treatment with bisoprolol (target dose 10 mg q.d.) followed by combination therapy with enalapril (target dose 10 mg b.i.d.), compared to the opposite order, showed similar effects on survival and hospitalization. By echocardiography, we evaluated the effects of these treatment strategies on cardiac structure and function. Methods: In a single-centre substudy, we compared the impact on left ventricular (LV) dimensions and ejection fraction (EF) of treatment with bisoprolol-first (n = 21) and enalapril-first (n = 19) in 40 beta-blocker and angiotensin-converting-enzyme-inhibitor naive patients, with stable, mild or moderate CHF (NYHA II-III) and LVEF

Originele taal-2	English
Pagina's (van-tot)	59-63
Aantal pagina's	5
Tijdschrift	International Journal of Cardiology
Volume	144
Nummer van het tijdschrift	1
DOI's	https://doi.org/10.1016/j.ijcard.2009.04.040
Status	Published - 24-sep.-2010

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@article{8923cb2ab00140d3bf46aa08a7c6eaf1,

title = "The effect of treatment with bisoprolol-first versus enalapril-first on cardiac structure and function in heart failure",

abstract = "Background: In CIBIS III, initiating chronic heart failure (CHF) treatment with bisoprolol (target dose 10 mg q.d.) followed by combination therapy with enalapril (target dose 10 mg b.i.d.), compared to the opposite order, showed similar effects on survival and hospitalization. By echocardiography, we evaluated the effects of these treatment strategies on cardiac structure and function. Methods: In a single-centre substudy, we compared the impact on left ventricular (LV) dimensions and ejection fraction (EF) of treatment with bisoprolol-first (n = 21) and enalapril-first (n = 19) in 40 beta-blocker and angiotensin-converting-enzyme-inhibitor naive patients, with stable, mild or moderate CHF (NYHA II-III) and LVEF",

keywords = "Heart failure, Drugs, Adrenergic beta-antagonists, Angiotensin-converting enzyme inhibitors, Cardiac remodelling, LEFT-VENTRICULAR DYSFUNCTION, INSUFFICIENCY BISOPROLOL, CIBIS-III, CARVEDILOL, TRIAL, METOPROLOL, INITIATION, INHIBITOR, FRACTION, THERAPY",

author = "{Van de Ven}, {Louis L. M.} and {van Veldhuisen}, {Dirk J.} and Michael Goulder and Zsolt Zilahi and Meyer, {Wilfried R.} and Ronnie Willenheimer",

year = "2010",

month = sep,

day = "24",

doi = "10.1016/j.ijcard.2009.04.040",

language = "English",

volume = "144",

pages = "59--63",

journal = "International Journal of Cardiology",

issn = "0167-5273",

publisher = "ELSEVIER IRELAND LTD",

number = "1",

}

TY - JOUR

T1 - The effect of treatment with bisoprolol-first versus enalapril-first on cardiac structure and function in heart failure

AU - Van de Ven, Louis L. M.

AU - van Veldhuisen, Dirk J.

AU - Goulder, Michael

AU - Zilahi, Zsolt

AU - Meyer, Wilfried R.

AU - Willenheimer, Ronnie

PY - 2010/9/24

Y1 - 2010/9/24

N2 - Background: In CIBIS III, initiating chronic heart failure (CHF) treatment with bisoprolol (target dose 10 mg q.d.) followed by combination therapy with enalapril (target dose 10 mg b.i.d.), compared to the opposite order, showed similar effects on survival and hospitalization. By echocardiography, we evaluated the effects of these treatment strategies on cardiac structure and function. Methods: In a single-centre substudy, we compared the impact on left ventricular (LV) dimensions and ejection fraction (EF) of treatment with bisoprolol-first (n = 21) and enalapril-first (n = 19) in 40 beta-blocker and angiotensin-converting-enzyme-inhibitor naive patients, with stable, mild or moderate CHF (NYHA II-III) and LVEF

AB - Background: In CIBIS III, initiating chronic heart failure (CHF) treatment with bisoprolol (target dose 10 mg q.d.) followed by combination therapy with enalapril (target dose 10 mg b.i.d.), compared to the opposite order, showed similar effects on survival and hospitalization. By echocardiography, we evaluated the effects of these treatment strategies on cardiac structure and function. Methods: In a single-centre substudy, we compared the impact on left ventricular (LV) dimensions and ejection fraction (EF) of treatment with bisoprolol-first (n = 21) and enalapril-first (n = 19) in 40 beta-blocker and angiotensin-converting-enzyme-inhibitor naive patients, with stable, mild or moderate CHF (NYHA II-III) and LVEF

KW - Heart failure

KW - Drugs

KW - Adrenergic beta-antagonists

KW - Angiotensin-converting enzyme inhibitors

KW - Cardiac remodelling

KW - LEFT-VENTRICULAR DYSFUNCTION

KW - INSUFFICIENCY BISOPROLOL

KW - CIBIS-III

KW - CARVEDILOL

KW - TRIAL

KW - METOPROLOL

KW - INITIATION

KW - INHIBITOR

KW - FRACTION

KW - THERAPY

U2 - 10.1016/j.ijcard.2009.04.040

DO - 10.1016/j.ijcard.2009.04.040

M3 - Article

SN - 0167-5273

VL - 144

SP - 59

EP - 63

JO - International Journal of Cardiology

JF - International Journal of Cardiology

IS - 1

ER -

The effect of treatment with bisoprolol-first versus enalapril-first on cardiac structure and function in heart failure

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