The aim of this thesis was to investigate both the early and late effects of cigarette smoke and nitrogen dioxide (NO2) exposure and the potential dampening effects of heme oxygenase-1 (HO-1) in animal models for COPD. Additionally, we investigated the role of the specific immune response in the inflammatory response in COPD, i.e. the involvement of B cells and regulatory T cells.
|Kwalificatie||Doctor of Philosophy|
|Datum van toekenning||8-nov-2008|
|Status||Published - 2008|