The simulation studies of the interplay of peptides with lipids

Juanjuan Su

The simulation studies of the interplay of peptides with lipids

Juanjuan Su

Moleculaire Dynamica

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Dit proefschrift richt zich op de wisselwerking tussen twee klassen van membraan actieve peptiden en membranen, namelijk de antimicrobiële peptiden Magainin 2, BP100, MSI-78 en MSI-103 en de amfipathische peptide Pex11-Amph, met behulp van moleculaire dynamica (MD) simulaties. Begrip van het samenspel tussen peptiden en membraan lipiden is belangrijk om fundamenteel inzicht te verkrijgen in vele biologische processen.

Originele taal-2	English
Kwalificatie	Doctor of Philosophy
Toekennende instantie	Rijksuniversiteit Groningen
Begeleider(s)/adviseur	Marrink, Siewert, Supervisor de Sousa Pereira Simoes de Melo, Manuel, Co-supervisor
Datum van toekenning	19-mei-2017
Plaats van publicatie	[Groningen]
Uitgever	University of Groningen
Gedrukte ISBN's	978-90-367-9810-5
Elektronische ISBN's	978-90-367-9809-9
Status	Published - 2017

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Title and contentsFinal publisher's version, 142 KB
Chapter 1Final publisher's version, 414 KB
Chapter 2Final publisher's version, 1,36 MB
Chapter 3Final publisher's version, 1,13 MB
Chapter 4Final publisher's version, 974 KB
Chapter 5Final publisher's version, 63,6 KB
Chapter 6Final publisher's version, 66,4 KB
Chapter 7Final publisher's version, 65,5 KB
Complete thesisFinal publisher's version, 3,5 MB
PropositionsFinal publisher's version, 35,9 KB

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title = "The simulation studies of the interplay of peptides with lipids",

abstract = "This thesis addresses the interplay between two classes of membrane active peptides and membranes, namely the antimicrobial peptides Magainin 2, BP100, MSI-78, and MSI-103 and the amphipathic peptide Pex11-Amph, by using molecular dynamics (MD) simulations. Understanding the interplay of peptides with membrane lipids is important to provide fundamental insight into many biological processes.",

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AB - This thesis addresses the interplay between two classes of membrane active peptides and membranes, namely the antimicrobial peptides Magainin 2, BP100, MSI-78, and MSI-103 and the amphipathic peptide Pex11-Amph, by using molecular dynamics (MD) simulations. Understanding the interplay of peptides with membrane lipids is important to provide fundamental insight into many biological processes.

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SN - 978-90-367-9810-5

PB - University of Groningen

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