The Stress of Lung Aging: Endoplasmic Reticulum and Senescence Tete-a-Tete

M L Koloko Ngassie, C A Brandsma, R Gosens, Y S Prakash, J K Burgess*

*Bijbehorende auteur voor dit werk

Onderzoeksoutputpeer review

4 Citaten (Scopus)
81 Downloads (Pure)


Beyond the structural changes, features including the dysregulation of endoplasmic reticulum (ER) stress response and increased senescence characterize the lung aging. ER stress response and senescence have been reported to be induced by factors like cigarette smoke. Therefore, deciphering the mechanisms underlying ER and senescent pathways interaction has become a challenge. In this review we highlight the known and unknown regarding ER stress response and senescence and their cross talk in aged lung.

Originele taal-2English
Pagina's (van-tot)150-159
Aantal pagina's10
Nummer van het tijdschrift3
StatusPublished - mei-2021

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